Apidra vs. NovoLog – What Is The Difference?

Apidra Versus Novolog
Apidra Versus Novolog

Apidra and NovoLog are two drugs mainly used for reducing the blood sugar level of people with diabetes . These drugs serve as rapid-acting insulin, and they share certain similarities but are subtly different. Both of them are great recommendations if you suffer from Type 1 or Type 2 diabetes. In this article, we want to review both drugs to give you a better idea about how they work, when you can take them and where to purchase them with affordable pricing. Although there are different types of insulin in use today, our focus will be limited to Apidra and NovoLog.

Random fact: NovoLog is known as NovoRapid in Canada. It is the exact same product, made from the same manufacturer but under a different name. 


Apidra and NovoLog are injectable insulins that are taken subcutaneously to reduce high blood sugar within diabetics. These drugs are essentially meant for people living with Type 1 and Type 2 diabetes. Type 1 diabetes is a medical condition that is caused by the pancreas’s inability to produce insulin to break down sugar in the bloodstream. Type 2 diabetes is similar to Type 1, but for this condition, the pancreas produces only a very limited amount of insulin, which is not enough to keep blood sugar in check.

Without the presence of sufficient insulin, glucose cannot be transformed into energy, so it remains in the bloodstream and leads to excess blood sugar  When blood sugar is too high in the bloodstream, it leads to life-threatening conditions that must be addressed before they spike out of control. To address this situation, drugs like Apidra and NovoLog is used


Apidra is a diabetes medication that is taken via injections. This drug is used to control blood sugar levels, and it contains insulin glulisine  Insulin glulisine is an analog drug that works in exactly the same way that naturally occurring insulin works in the body. Once this hormonal drug is injected, the effects begin to take hold because it works rather quickly. However, it only remains in the body for a relatively short time before it fades off.

This makes it an ideal choice for users who want to practice flexible dietary habits, as it allows them to have freedom with their meals without adhering to a strict timeline. Apidra vialsSolostar Pens and cartridges are readily available through our pharmacy. 



NovoLog is another diabetic drug that speeds up the process of pushing glucose into the blood cells for energy conversion. NovoLog is merely a brand name, just like Apidra, but the drug itself is insulin aspart  Insulin aspart can be taken in injectable form. This drug is injected into the fat tissue in the thigh area, buttock, stomach, or upper arm. Also, it can be taken before or after meals.

NovoLog is fast-acting insulin for blood sugar regulation and also does not last long in the body. If you want to keep sugar levels in control all day, you may need to use long-acting insulin. NovoLog vialsFlextouch and cartridges are available for purchase through our online pharmacy (prescription required). 

Novolog Insulin From Canada

Apidra vs. NovoLog: What are the Differences and Similarities?

These medications have certain similarities and differences. Let us review them.

Apidra vs NovoLog Similarities

Both of them are fast-acting insulins, so they start working as soon as they at injected into the body. On average, they start working after 15 minutes and peak after an hour, but their effects will remain for 2-4 hours before they wear out.

Another similarity between Apidra and NovoLog is the way they are taken. They are injected using injection pens or syringes filled medication from a vial. It can also be used through an a insulin pump  Please note, it is ill-advised to inject the same spot twice, as this can lead to side effects. 

Furthermore, they share similar symptoms, including sweating, dizziness, faster heartbeat, hunger, headache, nausea, etc. These symptoms are caused by a condition called hypoglycemia. Hypoglycemia is basically low blood sugar and occurs when the medication has broken sugar down to very low levels. However, hypoglycemia lasts for a short time and will fade away once the effect of the medication wears off. However, if you are at risk of a prolonged phase, your doctor will provide recommendations to prevent a reoccurrence.

Apidra vs NovoLog Differences

Apidra and NovoLog are different in certain aspects. For starters, Apidra is insulin glulisine, while NovoLog is insulin aspart. While Apidra is a fast acting insulin that kicks in within 15-20 minutes after you take it, NovoLog has a much quicker effect as it works within 5-10 minutes.

Another difference between the two is their cost. Apidra is sold at a slightly higher price than NovoLog. However, the longest Apidra will remain in the body is 4 hours, while NovoLog can last for as long as 5 hours.

Another difference is the age range which they are used for. Apidra is used to treat Type 1 and Type 2 diabetes in adults and children above 6 years old. As for NovoLog, it can be used for adults suffering from Type 1 and Type 2 diabetes as well as for children over 2 years old who have Type 1 diabetes.

General Reactions

Two users of the same drug may not react to them in exactly the same way, and this is the case with insulin as well. Therefore, it should come as no surprise to you if your doctor recommends that you switch from one insulin drug to another, to find the right one that triggers minimum reactions in you.

Apidra and NovoLog as Analog Insulin

You may have come across the term “analog.” Both Apidra and Novolog are analog drugs. An analog drug is a man-made drug that works in exactly the same way as a naturally occurring mineral. In the case of Apidra and NovoLog, both of them work just like insulin produced by the human pancreas, as they control blood sugar.

In the case of Apidra and NovoLog, once they are injected, they are absorbed into the bloodstream within minutes, and they cause an insulin surge by the pancreas, which will turn begin to break down blood sugar

Pros and Cons of Using Apidra

So what are the pros and cons of using Apidra to control blood sugar? Let’s take a look at a few of them below.

Pros of Apidra

– It is available in different forms

– It works really fast

– It does not affect your weight

– It can be injected before or after meals

– It can cause low blood sugar level within the first hour after a meal

Apidra Insulin Pros and Cons

Cons of Apidra

– It is quite expensive

– It requires stringent kidney and liver checks before it is prescribed

– It can only be injected using a special type of syringe

– It has to be injected several times a day

– It is only available in injectable forms

Pros and Cons of Using NovoLog

What are the pros and cons of using NovoLog to control blood sugar? Let’s take a look at a few of them.

Pros of NovoLog

– People living with kidney and liver conditions can use it, unlike other diabetic medications.
– It is available in different forms and dosages
– It has fast-acting effects and prevents sugar spikes throughout the day

Cons of NovoLog

– It is only available in injectable forms
– It may lead to fat accumulation and weight gain
– It requires constant sugar level checks
– It is harder to find the perfect dosage
– It may lead to hypoglycemia if it is not used consistently or you don’t have a strict diet timeline
– It exposes users to a higher risk of low blood sugar

NovoLog Pros and Cons

Where can I buy cheap Apidra and NovoLog?

Apidra and NovoLog insulin products can be quite expensive to many American Diabetics. Thousands of Americans are buying their insulin from Canada through prescription fulfillment services, such as Insulin Outlet  Our customers are saving up to 80% on their diabetic medications. Our success stories are unmatched, as we continue to change the lives of American Diabetics from coast to coast! You can find the best prices on Apidra (vials and SoloStar Pens) and NovoLog (vials and FlexPens) online through our pharmacy   

Which is Best Between Apidra and NovoLog?

Both of them are effective medications, and one cannot place one above the other. Furthermore, it is in your best interest to allow your doctor to prescribe one for you instead of choosing one for yourself. This is because they impact certain bodily functions. Also, each time you use it, you are at risk of hypoglycemia because it lowers blood sugar levels which may cause some unpleasant reactions. Please visit your healthcare professional and discuss your lifestyle and medical history. This information will help your doctor prescribe medication that is suitable to you. 

So while you may have your preferences, your doctor may have to conduct checks on your kidney and liver, especially if NovoLog is going to be the drug of choice. It is only after conducting an extensive test that the medical practitioner can tell which one will be right for you.

However, we admit that some patients may have their preferences after using Apidra and NovoLog, which is not a bad thing. But be open to discussing your feelings with your doctor and let him give you the go-ahead before you start using any of these drugs rather than doing so on your own.



Apidra- insulin glulisine injection, solution Apidra SoloStar- insulin glulisine injection, solution”. DailyMed. 6 December 2019. Retrieved 17 December 2020.

Garnock-Jones KP, Plosker GL (May 2009). “Insulin glulisine: a review of its use in the management of diabetes mellitus”. Drugs. 69 (8): 1035–57. doi:10.2165/00003495-200969080-00006. PMID 19496630. S2CID 41839395.

Heise T, Pieber TR, Danne T, Erichsen L, Haahr H. A pooled analysis of clinical pharmacology trials investigating the pharmacokinetic and pharmacodynamic characteristics of fast-acting insulin aspart in adults with type 1 diabetes. Clin Pharmacokinet. 2017;56(5):551-559. doi: 10.1007/s40262-017-0514-8.

NovoLog [prescribing information]. Plainsboro, NJ; Novo Nordisk Inc; 2018. www.novo-pi.com/novolog.pdf. Accessed December 17th, 2022.