How Long Does Mounjaro Stay In Your System?

how long does mounjaro last
A woman giving herself an insulin injection in the abdomen

Mounjaro (tirzepatide) is a prescribed injectable medication used in type 2 diabetes treatment. Similar to Ozempic, Mounjaro has been proven to be an effective weight-loss drug, helping patients manage their appetite and blood sugar levels. 

If you’re planning to discontinue taking Mounjaro, you might be wondering, how long does the drug stay in your body? 

Here’s all you need to know about this topic.

How Long Does Mounjaro Stay In Your System?

Mounjaro can stay in your system for as long as 30 days since your last dose. That is the time needed for your body to completely remove the drug from the system.

This prolonged period is due to the fact that Mounjaro is a long-acting medication with a half-life amounting to around 5 days. The half-life of a medication is the time needed for half of the drug to be removed from the system.

Of course, the exact time it will take for your body to fully metabolize and clear from Mounjaro depends on individual factors. Things like your metabolism, genetic predispositions, and other variables can extend or shorten this time.

What Is The Half-Life of Mounjaro?

As we stated earlier, the half-life of Mounjaro is 5 days. It’s important to keep in mind this number is not set in stone, and the half-life of this drug may differ for each individual. Mounjaro has a long half-life and is usually injected in weekly intervals (one dose per week).

Tips on How To Remove Mounjaro From Your System Faster

What to do to help your body clear from the medication in the shortest time possible? There are no golden shortcuts here, and there shouldn’t be. If there aren’t any medical contraindications, your body is capable of safely removing the medication on its own.

What you can do is adhere to some simple lifestyle changes in order to make this process as easy as possible. What are these changes?

Balanced Fatty Fish Diet

First and foremost, it’s always beneficial to stick to a healthy, green, rich in fish fats diet. Of course, your diet should be adjusted to your current health condition, which is why it’s best to create it with the help of a specialist.

But a good, balanced diet generally helps your body in recovery and supports good metabolism. It can promote good blood glucose levels as well as support your liver.

Fatty fish contain lots of omega-3 fatty acids, which come with a list of benefits, reducing inflammation and helping with symptoms of several autoimmune diseases.

By delivering your body all the nutrition and vitamins it needs, you’re giving it the best chance at dealing with all the other processes that take place, which includes clearing itself from Mounjaro.

No Alcohol Consumption

Alcohol is heavy on the liver, which means you want to avoid consuming it altogether (or at least in larger quantities) if you care about shortening the time needed for Mounjaro to leave your system.

Staying abstinent during the Mounjaro treatment or when you’re diagnosed with type 2 diabetes is a very beneficial change to make. Alcohol increases the chance of experiencing some side effects from the medication, as well as exposes you to a variety of health risks.

Avoiding Other Drugs and Supplements

The same way alcohol burdens your liver, so do the other drugs and supplements you might be taking. Of course, you shouldn’t stop administering medications that are necessary for your health and well-being. But it might be a good idea to limit the number of additional medications and supplements you’re taking for this period.

Always talk about including or excluding drugs and supplements with your doctor.


Mounjaro is a long-acting drug that stays in your body for around 30 days since your last dose. When you stop administering the medication, you can expect a month to pass before you’re completely clear from Mounjaro.

There is no healthy way to flush out the drug from your system, but you can introduce some positive lifestyle changes to help your body metabolize and remove Mounjaro faster.

If you’re an American citizen and you want to purchase the drug, consider ordering from Insulin Outlet pharmacy. Find and order Mounjaro from Canada at a more affordable price.


  1. Endocrine, Metabolic & Immune Disorders-Drug Targets (Formerly Current Drug Targets – Immune, Endocrine & Metabolic Disorders), Tirzepatide: A New Generation Therapeutic for Diabetes Type 2