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What is Fiasp?

Fiasp is a high-potency, mealtime insulin that lowers blood sugar in a fast-acting manner. Fiasp is an insulin-containing injection solution used to treat diabetes mellitus in adults, adolescents, and children aged one year and older. Fiasp is prescribed to help you manage your diabetes. Fiasp could be injected as long as 20 minutes after beginning a meal, up to 2 minutes before it starts. One to three hours after injection, the medicine’s maximum effect occurs, and the effect lasts for three to five hours. This medicine is generally most effective when used with intermediate-acting or long-acting insulin preparations. 

Fiasp should not be used if you are allergic to insulin or any other part of this medication.

Warnings and Precautions 

Consult your physician or pharmacist before taking Fiasp. In particular, you should be aware of the following: 

• Fiasp lowers blood sugar more rapidly than other mealtime insulins when low blood sugar (hypoglycemia). Having Fiasp injections may lead to hypoglycemia occurring earlier.

• Blood sugar levels that are too high (hyperglycemia) 

• If you are switching from another medication containing insulin, your doctor may have to adjust your insulin dosage. 

• If your insulin treatment is combined with pioglitazone (a type 2 diabetes oral antidiabetic medicine), it may lead you to experience other symptoms of heart failure such as shortness of breath, rapid weight gain, or edema). 

• Diabetic eye disorders, including diabetic retinopathy, may temporarily worsen with rapid improvements in blood sugar control. 

• Nerve damage pain – This occurs when blood sugar levels drop very quickly and usually last for a short time. 

If you start using your medicine for the first time, your body may accumulate more fluid around your joints. Your ankles may swell as a result. The swelling usually lasts only a short time. 

Make sure you are using the correct type of insulin – always check the label before each injection to prevent an accidental mix-up. 

Treatment with insulin can result in the body making antibodies to insulin (substances that attack insulin). The insulin dose will only very rarely need to be changed in this situation. 

Insulin requirements can be affected by certain conditions and activities. Consult your physician in regards to the following: 

• Diagnosis of kidney or liver problems, or problems with the adrenal, pituitary, or thyroid gland. 

• You may need to change your diet if you exercise more than usual or exercise more than usual, which will affect your blood sugar. 

• Keep taking your insulin if you are sick and consult your doctor. 

• Taking insulin injections properly can be affected by traveling over time zones if you’re going out of the country. 

Injection Site Warnings

The injection site should be rotated to the fat tissue under the skin to prevent needle stick injuries, including skin thickening, skin shrinkage, or lumps under the skin. Glucose may not be adequately absorbed if you inject into an area that has shrunk, thickened, or is lumpy. If your skin changes after the injection, you should talk to your physician. If you are currently injecting into these areas, tell your doctor before injecting in another place. It may be recommended that you check your blood sugar more regularly and adjust your insulin dosage or other antidiabetic medications. 

Additional Medicines and Fiasp

Any other medicines you are taking, have recently taken, or might should be discussed with your doctor. The insulin dose you take might have to change if your medication affects your blood sugar level. 

The following are the most common medicines that may affect insulin treatment. A fall in blood sugar level (hypoglycemia) can occur if you mix Fiasp with: 

• Oral or injectable medicines for diabetes (other than insulin) 

• Antibiotics that contain sulphonamides (used to treat infections) 

• Anabolic steroids (for example, testosterone) 

• Patients with high blood pressure or heart attacks can take beta-blockers. 

• salicylates (used for pain relief and to lower fever) 

• Monoamine oxidase inhibitors (MAOIs) (for treating depression) 

 • Heart problems, high blood pressure, and ACE inhibitors.

If you take the following, you may experience hyperglycemia (high blood sugar):

• Danazol (ovulation-inducing medicine) 

• Birth control pills (oral contraceptives) 

• Hypothyroidism (for thyroid conditions) 

• Growth hormone (for deficiency of growth hormone) 

• Glucocorticoids (like cortisone – to treat inflammation)

 • Sympathomimetics (e.g., epinephrine (adrenaline), salbutamol or terbutaline – if you have asthma)

 • Thiazides (when your body is retaining too much water or for high blood pressure). 

Acromegaly (excessive growth hormone) is treated with octreotide and lanreotide. These medications can affect your blood sugar levels. Consult your doctor or pharmacist if any of the above apply to you (or if you are unsure).

Important Information About Fiasp

Fiasp and Drinking Alcohol 

Your insulin needs may also change or fall when you drink alcohol as your blood sugar level changes. This means you need to check your blood glucose levels more frequently.

Breastfeeding and Pregnancy 

Ask your doctor for advice before taking this medicine if you are pregnant or think you may be pregnant. If you use this medicine during pregnancy and after delivery, you may need to adjust your insulin dosage. You usually require less insulin during the first three months of pregnancy and more during the remaining six months. Diabetes must be managed carefully during pregnancy. For your baby’s health, avoiding low blood sugar (hypoglycemia) is crucial. You will likely need the same amount of insulin you used before your pregnancy after having had a baby. 

Fiasp can be taken during breastfeeding with no restrictions. 

Operating and Driving Machines

Low blood sugar levels can affect driving or operating any machine or tool. Concentration and reaction time can be affected if your blood sugar is low. The consequences can be potentially deadly. 

If you or any diabetic you know, experience any of the following symptoms, contact your healthcare professional right away:

• You often experience low blood sugar

• You have difficulty recognizing low blood sugar.

An Overview of Fiasp’s Ingredients

Despite a small amount of sodium in each dose, this medicine is sodium-free.

Side Effects of Fiasp Insulin

As with all medicines, this one may cause side effects, although not everyone will experience them. 

With insulin treatment, hypoglycemia is very common (affects more than 1 in 10 people). Hypoglycemia can be very dangerous. You may become unconscious if your blood sugar level falls too low. Severe hypoglycemia could result in brain damage and even death. Take action immediately if you have symptoms of low blood sugar.  

The following factors can cause low blood sugar:

• Alcohol consumption; excessive insulin use; excessive exercise; eating too little or skipping meals.

A drop in blood sugar may present with the following symptoms: 

• Anxiety; tremors or nervousness; feeling unusually tired, weak, sleepy; feeling confused; difficulty concentrating; short-term changes in your sight. 

How to Deal With low Blood Sugar 

• Glucose tablets and high sugar snacks like fruit juice or sweets should be carried with you at all times when you suffer from low blood sugar (always have glucose tablets and high sugar snacks to treat low blood sugar). 

• If your blood glucose level still is less than four mmol/L after 15–20 minutes, retest and re-treat.

• Wait until your blood sugar level has stabilized or until the signs of low blood sugar have gone. Then continue your insulin treatment as usual.  

What Should Others do if you pass out?

You should tell everyone you spend time with that you have diabetes. Tell them what might happen if your blood sugar drops too low, including the possible risk of passing out. 

If you pass out, they must: 

• Attempt to turn yourself over, so you don’t choke

• Seek medical attention immediately 

• Never give you anything to eat or drink because you may choke. 

A glucagon injection may speed up your recovery after passing out. You can only receive one if you know how to administer it. 

Glucagon will cause you to crave sugar or a sugary snack as soon as you come around. 

It will be necessary for you to be treated in a hospital if glucagon injections do not work. When severe low blood sugar is not treated over time, it can lead to brain damage. The damage can be temporary or permanent. It can even result in death. 

Fiasp should not be used by anyone having a severe allergic reaction (including anaphylactic shock) to insulin or any of its ingredients (how often this occurs is unknown). Contact emergency medical services immediately. 

Allergic Reactions

Allergic reactions can present themselves in the following ways: 

• Local reactions (e.g., rash, redness, itching) spread to the rest of your body. 

• You suddenly feel unwell and sweaty 

• Feeling sick (vomiting) 

• Your breathing is difficult 

• Feeling dizzy or experiencing rapid heartbeat. 

Skin rashes and swelling of the face may occur due to allergic reactions. Up to 1 in 100 people may be affected by these reactions. You should notify a doctor if these symptoms worsen or do not improve within a few weeks.

Fiasp Storage

Ensure that children cannot see or reach this medicine. This medicine should not be used after the expiry date stated on the label and carton, after ‘EXP.’ indicates the end of that particular month. 

Before using

Refrigerate at two °C to 8°C. Never freeze. Do not store near a freezer. Protect your cartridge against light by keeping it in a carton. 

Upon first opening

The product should not be refrigerated after opening. Cartridges (Penfills) can be kept at room temperature (not above 30°C) for four weeks. Protect the cartridge from light by keeping it in the carton. 

After each injection, throw away the needle. Drugs should not be disposed of through household waste or wastewater. If you are no longer using the medicine, talk to your pharmacist about disposing of it. By doing so, you will help protect the environment.