Basaglar Cartridges 100 Units / mL

Basaglar Cartridge
Insulin Glargine
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Description

The Basaglar 100 Units/ml Cartridge is considered long-lasting insulin used to treat type 1 and type 2 diabetes. It delivers a steady flow of insulin throughout the day to effectively control blood glucose (sugar) levels to prevent complications from diabetes.

This type of insulin is a manufactured form that replaces insulin typically produced by the body and delivers glucose to the cells to use as energy. By lowering blood sugar levels, you can avoid diabetes complications such as eye damage, nerve problems, damage to the organs, or loss of limbs.

If you stop taking this medication altogether, you may experience complications such as high blood sugar levels.

Doctors generally prescribe this popular diabetes cartridge to accompany fast-acting insulin or other diabetes medications. Follow directions as instructed on the pack inside or as prescribed by your doctor. Dosages and duration should be based on a patient’s situation. Never skip or change your dose.

This medication should be used alongside your doctor’s healthy diet and regular exercise program to maximize results.

Your doctor or nurse should show you how to administer the injection subcutaneously (under the skin) into the thigh, abdomen, or deltoid. Use a different spot for injection every time to avoid any pitting, thickened skin, or lumps.

If you have low blood sugar levels, do not take this medication. It’s essential to inject the
correct dosage, monitor blood sugar levels regularly and have regular meals.

Notify your doctor if you have kidney, heart, or liver problems. If you are pregnant your breastfeeding, you should advise your doctor before using it.

Do not drink excessive alcohol while taking this medication, as it can lead to a dangerously low blood sugar level.

Basaglar is also available in injectable pens.

Warnings and Precautions

Hypoglycemia (low blood sugar) is the most common adverse effect of insulin, including Basaglar. Glucose monitoring is recommended for all patients with diabetes. Uncorrected hypoglycemic or hyperglycemic reactions can cause loss of consciousness, coma, or death.

Any change of insulin regimen should be made cautiously and only under medical supervision. Basaglar should not be used for intravenous or intramuscular administration.

Basaglar must not be mixed with any other insulin or diluted with any other solution because it might not work as intended. Basaglar shall not be used if it is not water-clear and colorless or if it has formed a deposit of solid particles on the cartridge wall.

Side Effects

Common side effects of Basaglar include low blood sugar (hypoglycemia), allergy activation (see allergic reactions tab for more information), injection site reactions, body fat redistribution, itching, rashes, swelling, weight gain, upper respiratory tract infection, runny or stuffy nose, back pain, cough, urinary tract infection, diarrhea, depression, or headache.

Serious side effects from Basaglar aren’t common, but they can occur. Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency.

Serious side effects and their symptoms can include the following: headache, confusion, anxiety, drowsiness, hunger, irritable mood (being easily upset), sweating, fast heartbeat, seizures, coma, fatigue (lack of energy), feeling weak, muscle cramps, abnormal heart rhythm, respiratory failure and paralysis.

If you experience side effects and are having trouble dealing with them, please contact your health care provider and notify them.

Allergic Reactions

In rare cases, a patient may be allergic to an insulin product. Severe insulin allergies may be life-threatening. If you think you have an allergic reaction, seek medical help immediately. Signs of insulin allergy include rashes all over your body,  shortness of breath, wheezing (trouble breathing), palpitations (rapid heartbeat), sweating, low blood pressure.

The active ingredient in Basaglar is insulin glargine (rDNA origin).  The nonmedicinal ingredients in the 3 mL cartridges and KwikPen are glycerin, m-cresol, zinc oxide, and water for injection. Hydrochloric acid and sodium hydroxide are added for pH adjustment.

If you experience a severe allergic reaction, please visit your nearest healthcare facility.

Instructions

Basaglar is a clear solution and looks like some fast-acting insulins. Always check for the name of the insulin on the carton and the cartridge label when you pick it up from the pharmacy to make sure it is the same as the one your doctor has recommended.

It is essential to use the Basaglar cartridge only with reusable insulin pens. Using the cartridge in any other injection pen not suitable for the Basaglar cartridge could lead to a mistake in dosing and cause medical problems for you, such as a blood glucose level that is too low or too high.

Although rare, technical problems with the cartridge can occur, which may prevent correct dosing. They include: broken, cracked, or damaged cartridges, air bubbles or foam, and blocked needles.

Preparation

To avoid medication errors, check the insulin cartridge label before each insertion.

Inspect the insulin cartridge. Basaglar should be a clear and colorless solution with no visible particles. Do not use it if you notice anything unusual in the appearance of the solution.

Make sure the insulin is at room temperature to minimize local irritation at the injection site.

Wash your hands thoroughly. 

Carefully follow the injection pen directions for loading the cartridge into the injection pen.

Missed Dose

If you have missed a dose of Basaglar or if you have not injected enough insulin, your blood sugar level may become too high (hyperglycemia). Check your blood sugar frequently. Do not take a double dose to make up for a missed dose, as this may lead to an overdose (see next tab). 

Overdose

If you have injected too much Basaglar, your blood sugar level may become too low (hypoglycemia). Check your blood sugar frequently. In general, to prevent hypoglycemia, you must eat more food and monitor your blood sugar.

Hypoglycemia may occur due to an excess of insulin relative to food intake, energy expenditure, or both.

In case of a drug overdose, contact a healthcare professional, hospital emergency department, or regional Poison Control Centre immediately, even if there are no symptoms.

Pregnancy

If you are planning to have a baby, are pregnant, or are nursing a baby, consult your doctor. Good control of diabetes is especially important for you and your unborn baby. Pregnancy may make managing your diabetes more difficult.

Storage

Unopened Basaglar cartridges or KwikPens should be stored in a refrigerator, between 2°C – 8°C. Keep Basaglar away from direct heat and light. Basaglar should not be stored in the freezer and should not be allowed to freeze. If Basaglar freezes, discard it.

Opened (In Use) Cartridge or KwikPen: The opened Basaglar cartridge or KwikPen in use should be stored at room temperature (below 30°C) for up to 28 days away from direct heat and light. If there is any remaining insulin after 28 days, discard it. The opened cartridge in use must never be removed from and reinserted into the injection pen. If Basaglar freezes discard it.

Do not use a Basaglar cartridge or KwikPen after the expiration date stamped on the label or if it is cloudy or contains visible particles.

Disposing

Dispose of used needles in a sharps container or a rigid plastic container with a secure lid. Do not throw needles directly into your household trash. Do not recycle the filled sharps container. Ask your healthcare professional about options available to dispose of the sharps container properly.