Fiasp Cartridges 100 Units/mL

Fiasp Cartridge
Insulin Aspart
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Description

Fiasp Cartridges contains 3 mL of 100 units/mL solution for injection, and cartons containing five units are available. Refillable PenFill cartridge devices such as NovoPen are exclusively compatible with Fiasp Cartridges.

Insulin Aspart is a fast-acting human form of insulin that effectively lowers blood sugar levels for type 1 and type 2 diabetes patients.

Two expedients added to the formulation include Vitamin B3 (niacinamide) and L-arginine. This is to increase the speed of absorption faster and stability when compared to other mealtime insulin’s. It works almost immediately after application.

Typically this insulin is paired with longer-acting insulin types (basal insulin) that work throughout the day (between meals and while you sleep).

Fiasp is a fast-acting mealtime insulin aspart formulation used to treat diabetes. Fiasp will start to lower your blood sugar within 20 minutes after starting a meal. Due to this fast action, Fiasp should typically be combined with intermediate- or long-acting insulin preparation.

Cartons of 5 units are available. Each Fiasp cartridge contains 3mL of 100 units/mL solution for injection. Each Fiasp Cartridge is exclusively compatible with refillable PenFill

 

Before Taking Fiasp

A healthcare provider must prescribe Fiasp. Would you please mention to your healthcare provider if you:

– have trouble with your adrenal, pituitary, or thyroid glands, your doctor may alter your insulin dose.
– Have an infection, fever, or have had an operation, you may need more insulin than usual.
– Suffer from diarrhea, vomiting, or eating less than usual you may need less insulin than average.
– Exercise more than usual or if you want to change your regular diet.
– Are ill: continue taking your insulin. Your need for insulin may change.
–  Go abroad: traveling over time zones may affect your insulin needs and the timing of your injections. Consult your doctor if you are planning such travel.
–  Are you pregnant, planning a pregnancy, or are breastfeeding don’t hesitate to get in touch with your doctor for advice.
Drive or use tools or machines: watch for signs of hypoglycemia. Your ability to concentrate or to react will be less during a hypoglycemic reaction. Please keep this in mind in all situations where you might put yourself and others at risk.

Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements, or alternative treatments.

Be sure to do research on insulin aspart before meeting your doctor.

Warnings and Precautions

Low blood sugar is the most common adverse effect of insulin products, including Fiasp.

If low blood sugar or high blood sugar reactions are not treated, they can cause loss of consciousness, coma, or even death.

Blood sugar levels should be monitored for all patients with diabetes.

Fiasp should be injected up to 2 minutes before the start of the meal. When necessary, Fiasp may be administered up to 20 minutes after starting the meal.

An accidental mix-up between Fiasp and other insulin products has been reported. Always carefully check the insulin label before each injection to avoid mix-ups between insulin products.

Do not dilute or mix Fiasp with other insulin products or solutions, except when given into your vein under medical supervision.

Fiasp should generally be used in a regimen with intermediate- or long-acting insulin (plus metformin for type 2 diabetes as recommended) or with insulin infusion pump therapy to maintain blood sugar levels.

Only use Fiasp if the solution looks water-clear and colorless.

Usage

Fiasp is for injection under the skin (subcutaneously) or continuous infusion in pumps. Administration in a pump will require comprehensive instruction by your healthcare professional. Do not inject into a vein or muscle.

Always vary the site you inject within the same region to avoid lumps. The best places to give yourself an injection are the front of your thighs, the front of your waist (abdomen), or the upper arm. Your insulin will work more quickly if you inject it around the waist.

You should always measure your blood glucose regularly. Talk about your insulin needs with your doctor and Diabetes Nurse Educator.

Do not change your insulin unless your doctor tells you to. Follow their advice carefully. If your doctor has switched you from one type or brand of insulin to another, your dose may have to be adjusted by your doctor.

Due to the faster onset of action, Fiasp should be injected up to 2 minutes before starting a meal. When necessary, Fiasp may be administered up to 20 minutes after starting a meal.

Side Effects

The most common side effect related to Fiasp is hypoglycemia which in some cases may be life-threatening.

– Heart failure and fluid retention may occur with the concomitant use of thiazolidinediones (TZDs). Dosage reduction or discontinuation may be recommended if any severe symptoms or complications such as heart failure are experienced.

– As with other insulins, the use of Fiasp insulin can lead to other life-threatening hypokalemia, which may cause ventricular arrhythmia, paralysis, and even death. It’s important to monitor potassium levels to prevent hypokalemia and consult your physician if treatment is necessary.

– Infusion set or pump malfunctions can lead to ketoacidosis or rapid onset of hyperglycemia.

– Other adverse reactions may include allergic reactions, injection site reactions, weight gain, lipodystrophy, rash, pruritus, and hypoglycemia.

Call your doctor for medical advice about side effects.

Allergic Reactions

The active ingredient in Fiasp is insulin aspart. The non-medicinal ingredients are arginine (as L-arginine HCl), disodium phosphate dihydrate, glycerol, metacresol, niacinamide (vitamin B3), phenol, water for injections, and zinc (as zinc acetate). Hydrochloric acid and sodium hydroxide may be added for pH adjustment.

If you have a severe allergic reaction to the insulin or any of the ingredients in Fiasp, stop using Fiasp and see a doctor straight away.

The signs of a severe allergic reaction may include: local reactions (e.g., rash, redness, and itching) spread to other parts of your body, you suddenly feel unwell with sweating, you start being sick (vomiting), you experience difficulty in breathing, or you experience rapid heartbeat or feeling dizzy.

Missed Dose

If you have missed a dose of Fiasp or not injected enough insulin, your blood sugar level may become too high (hyperglycemia). Check your blood sugar frequently.

Do not take a double dose to make up for a forgotten dose.

Overdose

You get hypoglycemia if your blood sugar gets too low. This might happen if you take too much insulin if you eat too little or miss a meal, if you exercise more than usual or if you drink alcohol.

The warning signs of hypoglycemia may come on suddenly and can include: cold sweat; cool pale skin; headache; slurred speech; fast heartbeat; feeling sick; feeling very hungry; temporary vision changes; drowsiness; unusual tiredness and weakness; nervousness or tremor; feeling anxious; feeling confused; and difficulty concentrating.

If you experience these signs, eat glucose tablets or a high sugar snack (sweets, biscuits, fruit juice) and then rest. Don’t take any insulin if you feel hypoglycemia coming on. If you can, measure your blood sugar if possible and rest. You may need to measure your blood sugar more than once. Relax until the signs of too low blood sugar have gone or when your blood sugar level has settled. Then carry on with your insulin as usual.

If severe hypoglycemia is not treated, it can cause brain damage (temporary or permanent) and even death. If you have hypoglycemia that makes you pass out, or if you get a lot of hypoglycemias, talk to your doctor. The amount or timing of your insulin dose, the amount of food you eat, or the amount of exercise you do may need to be adjusted.

Tell your relatives, friends, and close colleagues that if you pass out (become unconscious), they must turn you on your side and get medical help right away. They must not give you anything to eat or drink as it could choke you.

Storage

Not in use (unopened): If unopened, Fiasp PenFill should be stored in a refrigerator (36°F to 46°F [2°C to 8°C]) until the expiration date. If unopened but improperly stored outside of refrigerated conditions, begin in-use storage for a maximum of 4 weeks.

In use (opened): After first use, Fiasp PenFill can be stored at room temperature (below 86°F [30°C]) for a maximum of 4 weeks (28 days). Do not refrigerate Fiasp PenFill cartridges after first use.