Ozempic Semaglutide Injection (2mg/1.5mL)
Ozempic (Semaglutide) is an injectable medication used to help adults with type 2 diabetes control high blood sugar, avoid cardiovascular risks such as heart attack and stroke, and lose weight. Although it holds similar functionality as insulin pens, Ozempic is not a insulin medication. Please do not use this medication to mimic any insulin management used by vials or Kwikpens.
The drug Ozempic is a Glucagon-like Petide-1 Agonist of a class of drugs called Antidiabetics. Ozempic does not use the same formula as Trulicity. Although they both produce similar results, the differ in their properties. Semaglutide should not be used to treat insulin resistance, type 1 diabetes, or ketoacidosis. Currently, it is unknown if it can be used to treat people with pancreatitis or safe for people under the age of 18.
Similar to the hormone incretin, semaglutide is naturally produced in the body. A high glucose level triggers the release of insulin, which lowers blood sugar levels in the liver. It has long-lasting effects (similar to NovoLog) and is usually administered once a week.
In weight loss management, Ozempic is used. Visit our article Foods to Avoid While Using Ozempic for more details on Ozempic and dieting.
Ozempic also comes in 4mg pens.
Warnings and Precautions of Ozempic Pens
Ozempic is not meant to be used by patients with type 1 diabetes.
Before taking Ozempic, inform your doctor about your complete health history. Ozempic may not be prescribed if you have pre-existing issues such as an allergy to GLP-1 agonists if you’ve had diabetic retinopathy in the past, or have kidney disease. If you have severe kidney issues, your doctor may not prescribe Ozempic.
Do not share Ozempic pens with others, even if the needle has been changed. This can lead to spreading severe infections.
Ozempic has a boxed warning to alert patients and doctors to the possible risk of thyroid cancer associated with the medication. You should consult your physician regarding the potential side effects.
Make sure the people around you know you have diabetes and take medication to control it by wearing identification, such as an ID card, bracelet, or necklace.
If you already have a medical condition, taking Ozempic could make it worse.
There is a possibility that Ozempic (Semaglutide) will lead to kidney failure. Your doctor will be able to tell you how a kidney problem or impaired kidney function may affect your existing condition as well as what special monitoring is necessary.
As well as increasing your heart rate, Ozempic may increase your function. A heart condition (like arrhythmia or heart block) requires you to consult your doctor. Your medication dosage may be adjusted, and you will be closely monitored.
Hypoglycemia (low blood sugar)
In combination with Ozempic, sulfonylureas (e.g., gliclazide, glyburide) can cause hypoglycemia. Symptoms of hypoglycemia can include an increased heartbeat, headache, cold sweat, feeling nervous, numbness or tingling in your tongue or lips, lightheadedness, and confusion. Your doctor may adjust the dosage of medications you are taking.
Pancreatitis (inflammation of the pancreas)
Pancreatitis can be caused by Ozempic. An abdominal pain that is severe may be an indication of pancreatitis. Regardless of whether you are currently suffering from pancreatitis or not, you should notify your doctor immediately if you have had pancreatitis in the past.
The use of this medication should not be recommended to people with a family history of thyroid cancer or multiple endocrine neoplasia type two. If you have symptoms such as difficulty breathing, hoarseness or a lump on your neck, contact your physician right away. In patients, semaglutide may not cause thyroid cancers, such as medullary thyroid carcinoma (MTC).
The effectiveness and safety of Ozempic have not been established for children.
Apply Ozempic subcutaneously to the abdomen, thigh, or upper arm.
If a patient injects in the same area of the body every week, they should use a different injection site each time.
Ozempic should be inspected visually before use. Colorless, translucent, and clear are the desired characteristics. If particulates and coloration are present, do not use Ozempic.
When using Ozempic with insulin, instruct patients to administer as separate injections and never mix the products. It is acceptable to inject Ozempic and insulin in the same body region, but the injections should not be adjacent to each other.
In addition to its typical side effects, Ozempic may also cause severe ones in patients who are prescribed it. Prior to administering Ozempic, you should discuss in great detail your medical history, lifestyle, and medication intake with your doctor.
Common Side Effects
The most common side effects of Ozempic may include nausea, vomiting, diarrhea, stomach (abdominal) pain, and constipation. Talk to your healthcare provider about any side effect that bothers you or does not go away.
Severe Side Effects
One of the severe side effects is the inflammation of your pancreas (pancreatitis). If this occurs, stop using Ozempic and call your healthcare provider right away if you have severe pain in your stomach area (abdomen) that will not go away, with or without vomiting. You may feel pain from your waist to your back.
Vision changes are also another server-side effect. Tell your healthcare provider if you have changes in vision during treatment with Ozempic.
The use of Ozempic may lead to hypoglycemia. The side effects of low blood sugar include dizziness or light-headedness, blurred vision, anxiety, irritability, mood changes, sweating, slurred speech, hunger, confusion or drowsiness, shakiness, weakness, headache, fast heartbeat, feeling jittery, kidney problems (kidney failure).
In people who have kidney problems, diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration) which may cause kidney problems to get worse. It would be best if you drank juices to help reduce your chance of dehydration.
Allergic Reactions and Ozempic
As well as severe allergic reactions, Ozempic can cause stomach upset. If you experience any severe allergic reaction symptoms, including swelling of your lips, tongue, or throat, coughing, hemorrhaging, little or no breathing, severe rash or itching, fainting, or rapid heartbeat, stop using Ozempic and seek medical help immediately.
The active ingredient in Ozempic is semaglutide. The inactive ingredients are disodium phosphate dihydrate, propylene glycol, phenol, and water for injection.
Semaglutide use during pregnancy is not well-studied enough to determine its risk for adverse developmental outcomes.
In the case of poorly controlled diabetes during pregnancy, there are clinical considerations.
Semaglutide may cause potential risks to the fetus when exposed to it during pregnancy, according to studies in animals. If the potential benefit outweighs the potential risk to the fetus, Ozempic should only be used during pregnancy.
Semaglutide caused embryofetal mortality, structural abnormalities, and growth changes in pregnant rats when administered at levels below the maximum recommended human dose based on AUC.
Semaglutide administration during organogenesis resulted in early pregnancy losses and structural abnormalities that were below (rabbit) and five times (monkey) the MRHD. In both animal species, maternal body weight was significantly reduced (see Data).
The background risk of significant congenital disabilities for women who have pre-gestational diabetes and an HbA1c of >7 is estimated to be 6–10%. Women with an HbA1c of >10 are reported to be at risk for developing diabetes by 20–25%. Two to four percent and fifteen to twenty percent of clinically recognized pregnancies in the U.S. result in major birth defects or miscarriages, respectively
It is not known whether semaglutide is present in human milk, what effects it has on nursing infants, and how it affects milk production. The presence of semaglutide in lactating rats’ milk is not clinically relevant because of species-specific variations in lactation biology. There should be a consideration of breastfeeding’s developmental and health benefits along with the mother’s clinical need for Ozempic and any possible adverse effects of Ozempic on the breastfed infant or the underlying maternal condition.
Overdose and Ozempic
The patient’s clinical signs and symptoms should be considered when determining appropriate supportive treatment. The long half-life of Ozempic of approximately one week may require prolonged observation and treatment for these symptoms.
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