We will be closed Monday, May 20th due to a Canadian Holiday. Shipping will resume Tuesday

 More Info 

SAVE 10% OFF First Order With Coupon Code: WELCOME10


Call Toll Free

SAVE 10% OFF First Order With Coupon Code: WELCOME10


Xigduo (5mg/tab-1000mg/tab Tablets)


Xigduo - 5mg/tab-1000mg/tab
SKU: DP-15515 Category:


Xigduo 5mg/1000mg tablets contain dapagliflozin and metformin. In addition to lowering the level of sugar in your blood, dapagliflozin removes excess sugar from your body via your urine. Additionally, it can help prevent heart disease. The main action of metformin is to inhibit the liver’s production of glucose.

As part of a 5-mg/1,000-mg film-coated tablet, the Xigduo 5 mg/1,000 mg contains dapagliflozin propanediol monohydrate equivalent to 5 mg of dapagliflozin and 1,000 mg of metformin hydrochloride per tablet.

Dapagliflozin can also be found in the medication Farxiga.

People with type 2 diabetes can control high blood sugar with this medicine and a proper diet and exercise program. Diabetes can cause kidney damage, blindness, nerve damage, loss of limbs, and problems with sexual function. Your risk of a heart attack or stroke may also be reduced if you control your diabetes properly. Diabetes type 2 patients can also use this medication to treat kidney disease or heart failure. You may live longer and be less likely to suffer from heart failure if you take it. By restoring your body’s proper response to insulin, this medication works. As a result, your kidneys remove more sugar from your body, your liver produces less sugar, and your stomach and intestines absorb less sugar.

You can take Xigduo 5mg/1000mg tablets with or without food at any time of day, but it is best to take it at the same time every day. Your doctor will determine the dose. Do not stop taking it without consulting your doctor. Your blood sugar levels may rise, putting you at risk of serious complications like kidney damage and blindness. As recommended by your doctor, this medicine should only be used as part of a treatment program that includes a healthy diet, regular exercise, and weight loss.


If you have any allergies to dapagliflozin or metformin, tell your doctor or pharmacist before taking this medication. There is a possibility that this product contains inactive ingredients, which may cause allergic reactions or other problems. For more information, contact your healthcare professional.

You should inform your doctor or pharmacist about your medical history before using this medicine, especially if you suffer from breathing problems (such as asthma, obstructive lung disease), kidney disease, liver disease, alcohol abuse, yeast infections in the vagina or penis, dehydration, blood disorders (such as anemia, vitamin B12 deficiency).

When your blood sugar is extremely low or high, you may experience blurred vision, dizziness, or drowsiness. Until you are sure you can perform the activity safely, do not drive, operate machinery, or engage in any activity that requires alertness or clear vision.

You should limit alcohol consumption while taking this medication to prevent lactic acidosis, low blood sugar levels, and high ketone levels.

If you have a high fever, take water pills (diuretics such as hydrochlorothiazide), sweat excessively, have diarrhea, or vomit, you may suffer from dehydration and be at risk of lactic acidosis. In case of prolonged diarrhea or vomiting, stop taking this medication and contact your doctor immediately. Drink plenty of fluids to prevent dehydration, unless directed otherwise by your doctor.

Stress (such as fever, infection, injury, or surgery) can make controlling blood sugar more difficult. As a result of these conditions or any illness, eating less or not being able to eat can lead to a high ketone level while taking this medication. It may be necessary to change your treatment plan, to change your medication, or to test your blood sugar or ketones. Consult your doctor if these changes are required.

Tell your doctor or dentist about all the products you use (including prescription drugs, non-prescription drugs, and herbal products) before having surgery or X-rays using iodinated contrast. For the surgery/procedure, you may need to stop taking this medication for a short period of time. Please consult your doctor or dentist before undergoing surgery or undergoing a procedure.

It is possible that older adults may be more sensitive to the side effects of this drug, such as low blood sugar, dehydration, lactic acidosis, kidney problems, and low blood pressure.

It is important to use this medication only when clearly necessary during pregnancy. Consult your doctor about the risks and benefits (more information on pregnancy tab).

There is a possibility that pregnancy can cause or worsen diabetes. Manage your blood sugar during pregnancy with the help of your doctor. It is possible that your doctor will need to make changes to your diabetes treatment during your pregnancy (such as diet and medications, including insulin).

Metformin can alter the menstrual cycle (promote ovulation) and increase the risk of pregnancy. If you are taking this medication, you should consult your doctor or pharmacist about the use of reliable birth control.

There is a small amount of metformin in breast milk. Dapagliflozin may pass into breast milk. Breastfeeding should be discussed with your doctor.


Your pharmacist will provide you with a Medication Guide before you start taking this medication and every time you get a refill. Ask your doctor or pharmacist if you have any questions.

It is usually taken once daily with food in the morning, as directed by your doctor. Take the tablets whole. The tablets should not be crushed or chewed. As a result, all the drug is released at once, increasing the risk of side effects.

Dosages are determined by your medical condition, response to treatment, and other medications you may be taking. Tell your doctor and pharmacist about all products you use (including prescription drugs, nonprescription drugs, and herbal products). You may be instructed by your doctor to start this medication at a low dose and gradually increase it to reduce the risk of side effects (such as diarrhea, nausea, and vomiting). Make sure you follow your doctor’s instructions.

For best results, take this medication regularly. Take it every day at the same time to help you remember.

Consult your doctor if your condition does not improve or worsens (your blood sugar is too high or low).

Side Effects

You may experience headaches, diarrhea, nausea, vomiting, runny noses, and sore throats. Tell your doctor or pharmacist if any of these effects persist or worsen. Tell your doctor right away if stomach symptoms return after taking the same dose for several days or weeks. Lactic acidosis may cause stomach symptoms after the first few days of treatment.

Your stool may contain an empty tablet shell. Due to the fact that the medication has already been absorbed by your body, this effect is harmless.

It is important to remember that your doctor prescribed this medication because he/she believes that the benefits to you outweigh the risks. There are few serious side effects associated with this medication.

You should notify your doctor immediately if you experience any serious side effects, including: signs of urinary tract infection (e.g., burning/painful/regular/urgent urination, pink/bloody urine), and signs of kidney problems (e.g., change in the amount of urine, swelling legs/feet).

A new yeast infection in the vagina or penis may be caused by this medication. Occasionally, Fournier’s gangrene may occur in the genital/anal region. If you experience any signs of yeast infection in your vagina (such as unusual discharge/burning/itching/odor) or in your penis (such as redness/itching/swelling/discharge from your penis), please see your doctor as soon as possible.

Low blood sugar (hypoglycemia) is not usually caused by this medication. The drug may cause low blood sugar if you take it with other diabetes medications, if you do not eat enough calories, or if you exercise excessively. Consider lowering the dose of your other diabetes medication(s) with your doctor or pharmacist. Sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling hands/feet are all signs of low blood sugar. To treat low blood sugar, it is a good habit to carry glucose tablets or gel. You can quickly raise your blood sugar if you don’t have these reliable forms of glucose by eating table sugar, honey, or candy, or drinking fruit juice or non-diet soda. You should notify your doctor right away if you have a reaction to this product. Maintain a regular meal schedule and do not skip meals to prevent low blood sugar. You should consult your doctor or pharmacist if you miss a meal.

Hyperglycemia (high blood sugar) is characterized by thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, and fruity breath odor. Tell your doctor as soon as possible if you experience any of these symptoms. Diabetes medications may need to be adjusted by your doctor. If you are taking any diabetic medications such as insulin, please ensure you notify your healthcare professional.

You may become dehydrated while taking this medication. The kidneys can suffer serious damage as a result. Avoid dehydration by drinking plenty of fluids. You should contact your doctor or pharmacist right away if you are unable to drink fluids as usual, or if you are losing fluids (such as through vomiting, diarrhea, or excessive sweating). Tell your doctor right away if you experience any symptoms of dehydration, including urinating less frequently than usual, unusual dry mouth/thirst, fast heartbeat, or dizziness/lightheadedness/fainting. When rising from a sitting or lying position, get up slowly to reduce the risk of dizziness and lightheadedness.

Please note that this list does not include all possible side effects. Consult your doctor or pharmacist if you notice other effects not listed above.

For medical advice about side effects in the US, contact your doctor. The FDA can be contacted at 1-800-FDA-1088 or at www.fda.gov/medwatch if you experience any side effects.

Drug Interactions

Your medication may work differently or cause serious side effects if you have drug interactions. There are not all possible drug interactions listed on this page. Inform your doctor and pharmacist about all the products you use (including prescriptions, nonprescriptions, and herbal products). You should never start, stop, or change the dosage of any medicine without your doctor’s permission.

There are many drugs that can affect your blood sugar, making it more difficult to control. Consult your doctor or pharmacist before starting, stopping, or changing any medication. Your doctor should be informed of any changes in your blood sugar levels. Check your blood sugar regularly as directed. If you experience symptoms of high blood sugar or low blood sugar, contact your doctor right away. You may need to adjust your diabetes medication, exercise program, or diet. (See also previous Side Effects tab)

You may experience a fast/pounding heartbeat if your blood sugar drops too low (hypoglycemia) if you are taking beta-blocker medications (such as metoprolol, propranolol, glaucoma eye drops like timolol). The drugs do not affect other symptoms of low blood sugar, such as dizziness, hunger, or sweating.

Glucose will be detected in your urine. You should inform all your doctors and laboratory personnel that you use this medication.


911 should be called if someone has overdosed and has serious symptoms such as passing out or difficulty breathing. Otherwise, contact a poison control center immediately. Residents in the US can contact their local poison control center at 1-800-222-1222. Lactic acidosis may result from an overdose. Overdose symptoms include drowsiness, nausea, vomiting, diarrhea, rapid breathing, and slow/irregular heartbeat.

Missed Dose

When you forget to take a dose, take it as soon as you remember. In the event that you forget until it is time for your next dose, skip the missed dose and return to your regular schedule. In order to make up for a forgotten dose, do not take a double dose.

You should not stop taking this medicine without consulting your doctor first. Without this medicine, your blood sugar may rise.

You can ask your doctor, pharmacist, or nurse if you have any further questions about this medicine.


You should ask your doctor or pharmacist for advice before taking this medicine if you are pregnant or breastfeeding, think you may be pregnant, or are planning to become pregnant. If you become pregnant, you should stop taking this medicine, since it is not recommended during the second and third trimesters (the last six months). Pregnant women need to work with their doctors to determine the best way to control their blood sugar levels.

Before taking this medicine, talk to your doctor if you are or wish to be breast-feeding. This medicine should not be used by women who are breastfeeding. There is a small amount of metformin that passes into human milk. Human breast milk is not known to contain dapagliflozin.


Children should not have access to this medicine.

This medicine should not be used after its expiry date, which is listed on the blister or carton after ‘EXP’. Expiry dates refer to the last day of the month.

There are no special storage requirements for this medicine.

Wastewater and household waste should not be used to dispose of medicines. You can dispose of medicines you no longer need by asking your pharmacist. As a result of these measures, the environment will be protected.

Customer Reviews