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Yuflyma (Adalimumab)

1 pen for $1,484.37

Yuflyma - 80mg/0.8ml


SKU: GP-21 Category:


Yuflyma (adalimumab-aaty) reduces pain, inflammation, and skin symptoms associated with autoimmune conditions by inhibiting TNF alpha. A variety of diseases and conditions are treated with Yuflyma, including rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn’s disease, ulcerative colitis, plaque psoriasis, and hidradenitis suppurativa.

The immune system is responsible for fighting bacteria and viruses that cause diseases. An autoimmune disorder, however, is caused by an overactive immune system attacking itself, causing symptoms.

Inflammation is caused by tumor necrosis factor (TNF). The TNF blocker Yuflyma reduces pain, inflammation, and skin symptoms by inhibiting TNF. This is a biosimilar to Humira. Biosimilars are biological medicines that have a high degree of similarity to the original product. Biosimilars cannot be interchanged. An autoinjector or prefilled syringe can be used to administer Yuflyma, which is available as a high-concentration, citrate-free formulation.

Adalimumab can also be found in Amgevita, Idacio, Hulio and Hadlima.

Warnings & Precautions

Your immune system is affected by Yuflyma. Infections may be more likely to occur, even serious or fatal ones.

In case of fever, chills, aches, tiredness, cough, sores, diarrhea, or burning when you urinate, tell your doctor before or during treatment with Yuflyma.

Before starting Yuflyma, you should be tested for tuberculosis (TB), and your doctor should closely monitor you during treatment for signs and symptoms of TB.

TNF-blockers may increase the risk of developing cancer in children and adults.

In case of fever, chills, sweats, muscle aches, tiredness, cough, bloody mucus, skin sores, diarrhea, or constantly tired, tell your doctor before using Yuflyma.

Please let your doctor know where you live and if you have traveled recently or will travel shortly. Some areas of the world are prone to infections.

In rare cases, Yuflyma can cause liver, spleen, and bone marrow lymphomas (cancers). Mostly, young men and teenagers with Crohn’s disease or ulcerative colitis are affected. Lymphoma may be more prevalent in people with inflammatory autoimmune disorders. It would help if you discussed your own risk with your doctor.

FDA-approved conditions are the only ones for which Yuflyma should be used in specific age groups. Before starting Yuflyma treatment, children should be up-to-date on all childhood immunizations.

You should tell your doctor if you have ever experienced any of the following:

  • You have tuberculosis (or anyone in your household has tuberculosis);
  • Infection that lasts a long time;
  • A cancerous tumor;
  • Yuflyma can cause hepatitis B to return or worsen);
  • diabetes;
  • Failure of the heart;
  • The presence of numbness or tingling or the presence of a nerve-muscle disorder such as multiple sclerosis or Guillain-Barre syndrome;
  • Latex allergy;
  • If you are scheduled for major surgery,
  • Any vaccine you have recently received or are scheduled to receive.

Yuflyma Uses

The FDA has approved Yuflyma for the following uses:

  • When used alone, with methotrexate, or with other medications, it is effective against moderate to severe rheumatoid arthritis in adults.

  • It is used alone or in combination with methotrexate for the treatment of juvenile idiopathic arthritis (moderate to severe polyarticular) in children over the age of two.

  • It can be used alone or in conjunction with other medicines to treat psoriatic arthritis in adults.

  • Ankylosing spondylitis in adults.

  • Adults with hidradenitis suppurativa (moderate to severe).

  • Adults and children 6 years and older with moderate to severe Crohn’s disease.

  • Adults with ulcerative colitis (moderate to severe). People who stop responding to or cannot tolerate TNF-blocker medicines may benefit from Yuflyma products.

  • Adults suffering from plaque psoriasis who have the condition in many areas of their body may benefit from injections or pills (systemic therapy) and phototherapy (treatment using ultraviolet light alone or with pills).

Side Effects

An injection site may be red, itchy, painful, or swollen. If any of these effects persist or worsen, contact your doctor immediately. Your doctor prescribed this medication because they determined its benefits outweighed any side effects it may cause. The side effects of this medication are generally not severe in most people who use it.

The following signs of infection may occur while you are taking this drug: a sore throat that does not go away, a cough that does not go away, fever, chills, night sweats, difficulty breathing, frequent urination, unusual vaginal discharge, and white patches in the mouth (oral thrush).)

In case of severe side effects, tell your doctor right away

  • A fast, irregular, or pounding heartbeat;
  • A new or worsening heart failure symptom (such as shortness of breath);
  • Ankles/feet swelling, unusual fatigue, unexpected weight gain);
  • The presence of blood in the stool;
  • Changes in mental/emotional state;
  • Severe headaches;
  • Bruising/bleeding is easy;
  • The legs are swollen or painful;
  • A tingling or numb sensation in the hands, arms, legs, or feet;
  • A feeling of unsteadiness;
  • Unexplained muscle weakness;
  • Speaking, chewing, swallowing, and facial movements are difficult;
  • Changes in vision.


When exposed to hepatitis B virus, adalimumab may cause serious (possibly fatal) liver disease. You should be monitored for several months after your last treatment and during treatment. In case of liver damage, seek medical attention right away, including nausea/vomiting that doesn’t stop, loss of appetite, stomach/abdominal pain, yellowing eyes/skin, and dark urine.

Seizures and chest pain are severe side effects. Get medical help immediately.

Allergic reactions are rare with this drug. When you have severe allergic reactions, such as rashes, itching, swelling (especially of the mouth/throat), dizziness, and trouble breathing, seek medical attention immediately.

Possible side effects are not listed here. Contact your doctor if you notice other effects.

Yuflyma Forms

Depending on the age, severity, and condition treated, Yuflyma is given at different doses and frequencies.

Yuflyma is available in the following forms:

  • Prefilled Yuflyma auto-injectors (Yuflyma AI): 40 mg in 0.4 mL
  • A prefilled syringe with a safety guard that contains 40 mg/0.4 mL of Yuflyma 
  • Prefilled Yuflyma Syringe: 40 mg/0.8 mL


Yuflyma may harm unborn babies. Consult your doctor if you are pregnant or plan to become pregnant. Be sure your doctor knows if you use Yuflyma during pregnancy, mainly before your baby receives any vaccinations.

If you use Yuflyma while breastfeeding your baby, it may not be safe for you to do so. When you are on Yuflyma, ask your doctor if there are any risks or what is the best way to feed your baby.

Storing Yuflyma

The original carton of this medicine should be stored in the refrigerator at 36°F to 46°F (2°C to 8°C).

Keep away from freezing. Keep your medicines properly stored during travel if you are traveling.

If it has frozen, throw it away. Extreme temperatures should be avoided.

Be careful not to shake.

If Yuflyma is traveling, it can be stored at room temperature up to 77°F (25°C) for up to 30 days, protected from light.

If Yuflyma is not used within 30 days, it should be discarded. In the space provided on the carton and dose pack, note the date when the medicine was first removed from the refrigerator.

Disposing Yuflyma

Sharps containers can be used to dispose of used needles, syringes, and autoinjectors to prevent needlestick injuries. If you don’t have an FDA-cleared container, you can use a heavy-duty plastic container you have at home. When your container is almost full, check your local laws and guidelines for disposal.

Yuflyma Cost & Discounts

Yuflyma can be used as an alternative for Humira. Humira is known to be one of the most expensive medications in the USA, hence why people would use Yuflyma as an alternative.

Insulin Outlet provides Americans with a discounted rate on Yuflyma. If this is your first order with Insulin Outlet, be sure to take advantage of the welcome10 coupon code and save 10% on your first order! For other coupon options, feel free to contact us and speak to one of our friendly customer service agents!

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