Estradot (Estradiol)

8 Patches for $38.18

Estradot 25 - 25mcg

Estradot 37.5 - 37.5mcg

Estradot 50 - 50mcg

Estradot 100 - 100mcg



Estradot patches are estrogen replacement therapy medications. As an anti-menopausal agent, it manages abnormal uterine bleeding, hot flushes, sweating, and chills related to menopause.

A female hormone produced by the ovaries is estrogen, a type of estrogen. During menopause, the ovaries produce less estrogen, resulting in hot flashes (sudden, extreme feelings of heat) and vaginal dryness. Menopause usually occurs around 50 years of age, but some women may undergo it earlier for various reasons, including surgery.

When an estradiol patch is applied to your skin, it releases estradiol into your blood through the skin. Women who have not had a hysterectomy (removal of their uterus or womb) must also take another female hormone called progestin while they are taking this medication to prevent complications associated with taking estrogen alone.

Osteoporosis can also be prevented with some forms of the estradiol patch when estrogen levels are low. Using the estradiol patch may help slow down further bone loss in situations where bone loss or fractures have already occurred. Along with calcium supplements, quitting smoking, and regular weight-bearing exercise, it prevents osteoporosis.

How To Apply

Below is a general step-by-step on how to apply the Estradot patches.

Select a clean, dry area of intact skin that is not oily, damaged, irritated, or exposed to the sun. Do not apply to the same spot on the skin twice.
Rather than using scissors, tear open the pouch containing the patch – it will become useless if you accidentally cut it.
The protective layer should be removed. The patch should be applied to the selected area as soon as possible. Touching the adhesive should be avoided.
Make sure the patch is firmly affixed to the skin around its edges by holding it in place for about 10 seconds.

If you need to change the patch, remove the old one carefully, fold it in half so that the adhesive sides stick together, and throw it away or take it to the pharmacy for proper disposal. Pets and children should not be allowed to access it. Rub your skin gently if adhesive remains on it.

The patch is not affected by bathing, showering, swimming, or other contact with water. The patch may, however, loosen when exposed to hot water or steam. Reapply your patch if it falls off. Apply a new patch if that doesn’t work.



Any unusual or allergic reaction to this group of medicines or any other medicines should be reported to your doctor. Please inform your healthcare professional if you have any other allergies, such as allergies to dyes, preservatives, or animals. Read the label or package ingredients carefully when purchasing non-prescription products.


It is not recommended to use this medicine before puberty. It is possible to stop bone growth early. Girls and boys can develop breast growth. Girls can experience vaginal changes, including bleeding.

This medicine may be used to start puberty in teenagers with certain types of delayed puberty.


People over the age of 65 are susceptible to the effects of estrogen. As a result, there may be an increased risk of side effects during treatment, particularly strokes, invasive breast cancers, and memory problems.

Side Effects

Common Side Effects

Most side effects do not require medical attention (report them if they persist or are bothersome):

Breast pain or tenderness
Hair loss
Stomach pain

Severe Side Effects

The following side effects should be reported as soon as possible to your healthcare team:

An allergic reaction may cause a rash, itching, hives, or swelling of the face, lips, tongue, or throat.
Pain, swelling, warmth in the leg, shortness of breath, and chest pain are all symptoms of a blood clot.
Changes in breast tissue, lumps, redness, pain, or discharge from the nipple.
Symptoms of gallbladder problems include severe stomach pain, nausea, vomiting, and fever.
Blood pressure rises.
The symptoms of liver damage include pain in the right upper belly, nausea, light-colored stool, dark yellow or brown urine, yellowing of the skin or eyes, and unusual weakness or fatigue.
Stroke. Sudden numbness or weakness of the face, arms, or legs. Difficulty speaking, confusion, unable to walk, loss of coordination or balance. Dizziness, severe headaches, vision changes.
Vaginal discharge, itching, or odor that is unusual.
Menopause bleeding, pelvic pain.


This medication should not be taken with any of the following:

A variety of aromatase inhibitors are available, including aminoglutethimide, anastrozole, exemestane, letrozole, and testolactone.

The following medications may also interact with this medication:

●  Carbamazepine
●  Clarithromycin and erythromycin are examples of certain antibiotics
●  Certain antiviral medications for HIV or hepatitis
●  Ketoconazole, itraconazole, and posaconazole are medications used for treating fungal infections
●  Itraconazole and ketoconazole are medications used for treating fungus infections
●  Phenobarbital
●  Raloxifene
●  Rifampin
●  St. John’s Wort
●  Tamoxifen

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.


A closed container away from heat, moisture, and direct light is the best place to store the patches at room temperature.

Medicine should be stored at room temperature, away from heat, moisture, and direct light. Don’t let it freeze.

Children should not be allowed to access this product.

Medicine that is outdated or no longer needed should not be kept.

If you don’t intend to use a medicine, ask your healthcare professional how to dispose of it.


It is not recommended to use estrogen during pregnancy or after giving birth. It is unlikely that a woman will become pregnant or maintain a pregnancy during menopause.

It has been shown that certain estrogens can cause severe congenital disabilities in humans and animals. When they reached childbearing age, some daughters of women who took diethylstilbestrol (DES) during pregnancy developed reproductive (genital) tract problems and, rarely, cervix or vaginal cancer. The urinary-genital tract problems of some sons of mothers who took DES during pregnancy have been reported.

Nursing mothers should not use this medicine. Breast milk contains estrogens, and their possible effects on a baby are unknown.

Missed Dose

You should apply a missed dose as soon as possible if you miss it. Do not apply more than the next dose if it is almost time for your next dose. Double or extra doses should not be used.

Customer Reviews