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Step 1
Choose the appropriate Humalog dose and quantity and add it to the cart. Additional diabetes supplies may also be added as needed.
Step 2
Patients must upload a clear photo or PDF during checkout for all prescription medications.
Step 3
A licensed pharmacist will review the order and verify the prescription.
Step 4
The order is then packed in temperature-controlled packaging to maintain its integrity during transit once it is approved. Delivery typically takes 3-5 business days.
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Humalog is a rapid-acting mealtime insulin used by people with type 1 and type 2 diabetes to help manage post-meal blood sugar spikes. Thousands of patients across the U.S. choose to order medications like Humalog from Insulin Outlet because prices can be significantly lower – often up to 80% less than typical U.S. pharmacy costs. A valid prescription is required. Insulin Outlet works only with licensed Canadian pharmacies to ensure every patient receives authentic and carefully handled medication at a more affordable price.
| Active Ingredient | Insulin Lispro |
|---|---|
| Type | Rapid-Acting |
| Manufacturer | Eli Lilly and Company |
| Onset | Within 15 minutes |
| Duration | About 4-6 hours |
| Form |
Note: U-200 Humalog can only be purchased in the form of KwikPens (not vials). |
| Origin | U.S. |
| Administration | Subcutaneous injection |
| Dosage | Individualized per prescription |
| Dosage Frequency | With meals (as prescribed) |
| Storage |
|
Humalog is a type of mealtime insulin that is used for patients with either type 1 or type 2 diabetes. Patients taking this medication use it to help them with their blood sugar control. This specific type of insulin is considered to be rapid-acting. This means that it has a quicker onset time compared to other insulins. However, it lasts a shorter duration. This medication is usually taken either 15 minutes before meals or immediately after starting meals.
Humalog can be found in a few different dosages and strengths. Humalog is produced in two concentration options – 100 units per mL and 200 units per mL. This insulin may be found and purchased as 10 mL vials or 3 mL prefilled pens. It is also supplied as 3 mL KwikPens or can be found in the form of 3 mL cartridges. Humalog may also be used with a Tempo Pen. U-200 Humalog can only be purchased in the form of KwikPens – not vials. This medication is only available in the form of subcutaneous injection and starting doses are individualized by the patient’s clinicians (there are no universal doses).
There is not an exact dosage recommendation for this medication to be taken by every patient. However, the amount prescribed is often determined by the patient’s body weight and a few other factors – like pre-meal blood sugar levels and the carbohydrates in the meal being consumed. A starting dose of 4 units or 10% of the patient’s body weight is often recommended as a starting dose for type 2 diabetes patients.
Humalog is to be used usually 15 minutes before meals or immediately after the meal. This medication should never be taken on an empty stomach or without food. Patients should instead follow their clinician’s direction on when to take this medication around meals to make sure they do not increase the risk of developing hypoglycemia. Glucose levels should also be checked prior to taking the medication. Patients should make sure to wash their hands and gather all necessary supplies before taking the medication. Insulin that is cloudy or has particles should not be used. The same goes for if the color is not clear.
New needles should be used for each injection and patients should follow the priming and administration instructions given to them by their prescriber. Humalog may be injected into the upper arm or leg. It may also be given under the skin of the buttocks or the stomach. Humalog should only be injected under the skin – not into a muscle or vein. These sites should also be rotated. Needles should be properly disposed of after use.
Patients should not use this medication if they are showing any symptoms of low blood sugar. They should also avoid the medication if they are allergic to insulin lispro or any of the other ingredients in the medication. Needles for this medication should also never be reused or shared. Doing so may lead to a serious infection. Patients should also never change the insulin type that they are taking or use a syringe to remove medication from a prefilled pen.
Patients should let their healthcare provider know about any medical conditions (past or present) in their family or personal history before starting the medication. This includes histories of:
Doctors should also be aware of any medications (especially TZDs) or supplements the patient is taking and if the patient is pregnant/planning to become pregnant or breastfeeding. The use of TZDs may also increase the risk of heart failure for patients using this medication since it can lead to increased fluid retention.
Hyperglycemia or hypoglycemia can occur in patients who are taking this medication – especially if they are undergoing a change to their insulin regimen. This medication should never be used during hypoglycemia episodes and changes to insulin doses/strengths or meal/activity patterns should be accompanied by increased blood glucose monitoring. The chance of developing hypoglycemia while taking Humalog also increases for patients taking other medications like antidiabetic agents or ACE inhibitors at the same time.
The same goes for patients combining Humalog with medications like:
The most common side effects for this Humalog insulin are:
Some patients may also experience more serious side effects – although these side effects are less likely to occur. These side effects include:
Patients experiencing any of these side effects should seek immediate medical attention.
Missed doses of this medication may be used as soon as remembered as long as it is right after a meal. Patients should contact their healthcare provider if they are unsure if too much time has passed. Doses should never be doubled to make up for any that were missed. Patients who overdose may be able to avoid complications by eating or drinking something with high sugar content. However, patients experiencing symptoms like difficulty breathing/fainting or seizures should get immediate medical attention.
Unopened Humalog should stay in the refrigerator at 36° to 46°F (2° to 8°C) and remains usable until the expiration date on the package. Opened prefilled pens can remain at room temperature but must stay below 86°F (30°C). A vial that has been opened may be stored in the fridge or kept at room temperature. Humalog must remain unfrozen and any frozen insulin should not be used. Store Humalog out of direct light and away from sources of heat. Discard opened vials, pens, and cartridges after 28 days – regardless of any remaining insulin.
| Insulin | Type | Manufacturer | Duration | Onset Time | Concentration | Injection Device |
|---|---|---|---|---|---|---|
| Humalog | Rapid-Acting | Eli Lilly and Company | 4-6 hours | About 15 minutes | U-100 or U-200 |
Note: U-200 Humalog can only be purchased in the form of KwikPens (not vials). |
| NovoLog | Rapid-Acting | Novo Nordisk | 4-6 hours | About 10 minutes | U-100 |
|
| Admelog | Rapid-Acting | Sanofi | 4-6 hours | About 15 minutes | U-100 |
|
Patients buying their medication from Insulin Outlet experience:
Buy Humalog vials and other forms from Canada today.
Yes. A valid prescription is required for all Humalog orders. Patients must upload a clear photo or PDF of their prescription during checkout so a licensed pharmacist can review and approve it before shipping.
Yes. Insulin Outlet ships Humalog directly to U.S. patients from licensed Canadian pharmacies. All orders are packed in temperature-controlled packaging to protect the medication during transit.
Humalog should stay in the refrigerator at 36° to 46°F (2° to 8°C) and remains usable until the expiration date on the package. Opened pens may stay at room temperature – provided they stay under 86°F (30°C) – and should be finished or discarded within 28 days.
Yes. These medications are the same as it is Lilly-manufactured insulin lispro. Both medications contain the same main ingredients and are made by the same manufacturer. Packaging may look slightly different. However, the medication’s quality/safety and effectiveness are the same.
Humalog (insulin lispro) and NovoLog (insulin aspart) are both rapid-acting mealtime insulins that start working within minutes and help control post-meal blood sugar. However, the biggest difference is that NovoLog uses a different main ingredient and may begin working slightly faster for some patients.
Humalog vials last until the expiration on the bottle or for up to 28 days after first use. The number of doses a patient will get from the bottle varies by patient and vial size.
Disclaimer: The information provided on this page is for educational and informational purposes only and is not intended to replace professional medical advice or treatment. Humalog is a prescription medication that must be used exactly as directed by a licensed healthcare provider.
American Diabetes Association. (2019, December 16). 9. Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes – 2020. Diabetes Care, 43(Supplement_1), S98–S110. https://doi.org/10.2337/dc20-s009
Billingsley, A. (2023, July 20). Is There a Humalog Generic? 5 Facts to Know about Admelog and Insulin Lispro. GoodRx. https://www.goodrx.com/admelog/humalog-generic
FDA Approves Sanofi’s Admelog® (insulin lispro injection) – Dec 11, 2017. (2017, December 11). Sanofi. https://www.news.sanofi.us/2017-12-11-FDA-Approves-Sanofis-Admelog-R-insulin-lispro-injection
HIGHLIGHTS AND PRESCRIBING INFORMATION. (2013). FDA. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/020563s115lbl.pdf
HIGHLIGHTS AND PRESCRIBING INFORMATION. (2015). FDA. https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/020986s082lbl.pdf
HIGHLIGHTS OF PRESCRIBING INFORMATION. (2025). Lilly. https://pi.lilly.com/us/humalog-pen-pi.pdf
Sison, G. (2021, May 7). Humalog vs. Novolog: Differences, similarities, and which is better for you. The Checkup. https://www.singlecare.com/blog/humalog-vs-novolog/
HUMALOG (HU-ma-log) KwikPen® (insulin lispro) injection, for subcutaneous use 3 mL single-patient-use pen (100 units per mL). (n.d.). Lilly. https://pi.lilly.com/us/humalog-kwikpen-um.pdf
INSTRUCTIONS FOR USE HUMALOG (insulin lispro) injection, for subcutaneous use. (n.d.). Eli Lilly and Company. https://pi.lilly.com/us/humalog-vial-ifu.pdf
Insulin Lispro injection. (2025, September 29). Cleveland Clinic. https://my.clevelandclinic.org/health/drugs/22669-insulin-lispro-injection
Marshall, H. (2022, April 23). Humalog (insulin lispro). https://www.medicalnewstoday.com/articles/humalog
Weiser, P. (2022, April 23). Humalog dosage. https://www.medicalnewstoday.com/articles/drugs-humalog-dosage
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×As we enter the warmer summer months, we are making minor adjustments to our shipping protocols to ensure you receive your medications in the best possible condition.
Due to higher seasonal temperatures during transit, we are implementing the following changes:
Why are we doing this?
While these medications are generally stable at room temperature for 15 to 30 days, shorter shipping cycles and increased insulation mitigate heat exposure. These proactive steps significantly reduce the need for reshipments and guarantee your medication arrives safely.