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Tazorac (Tazarotene)



SKU: DP-9349 Category:


Tazorac is a prescription medication that contains the active ingredient tazarotene. It is a retinoid, which is a derivative of vitamin A. This cream and gel are formulated as a topical treatment for various skin conditions, including acne vulgaris and plaque psoriasis. The is typically available in different strengths, allowing healthcare professionals to tailor the treatment to the specific needs of the patient.

This medication is primarily used by individuals who struggle with acne and psoriasis. Acne is a common skin condition characterized by the presence of pimples, blackheads, and whiteheads. It can affect people of all ages, from teenagers to adults. Psoriasis, on the other hand, is a chronic autoimmune disease that leads to the rapid buildup of skin cells, causing red, scaly patches to develop on the skin. Tazorac has shown remarkable effectiveness in improving these conditions and providing relief to those who suffer from them.

Tazorac works by regulating the growth of skin cells and reducing inflammation. The active ingredient, tazarotene, binds to specific receptors in the skin cells and modulates gene expression, leading to the normalization of cell growth and differentiation. By normalizing cell turnover, Tazorac helps prevent the formation of acne lesions and promotes the shedding of psoriatic scales. Additionally, it possesses anti-inflammatory properties that help reduce redness and swelling associated with these skin conditions.

Warnings and Precautions

While Tazorac can be effective in improving the appearance of acne, it’s important to be aware of the warnings and precautions associated with its use.

  • Use as directed: Follow the instructions provided by your healthcare professional or the product label. Applying more than the recommended amount or using it more frequently will not lead to faster results and may increase the risk of side effects.
  • Pregnancy and breastfeeding: Tazorac with your healthcare provider for suitable alternatives.
  • Allergic reactions: Some individuals may experience allergic reactions to Tazorac. If you notice symptoms such as severe itching, rash, or swelling, discontinue use and seek medical attention immediately.
  • External use only: Tazorac is for external use only and should not be ingested. If accidental ingestion occurs, seek medical help right away.
  • Start with a small amount: When starting Tazorac, it is recommended to apply a small amount to a small area of the skin to test for sensitivity or adverse reactions. If no significant reaction occurs, you can proceed with the regular application.
  • Avoid contact with eyes, mouth, and nostrils: Tazorac should not come into contact with sensitive areas such as the eyes, mouth, or nostrils. If accidental contact occurs, rinse thoroughly with water.
  • Use sunscreen: Tazorac can increase the skin’s sensitivity to the sun, making it more prone to sunburn. It is essential to apply sunscreen with a high SPF before sun exposure and wear protective clothing when outdoors.
  • Avoid other skin irritants: To prevent excessive irritation, it is advisable to avoid using other potentially irritating skincare products, such as abrasive cleansers or toners, while using Tazorac.

Side Effects

By understanding these potential risks, you can make informed decisions about your skincare routine and consult with your healthcare provider if necessary.

Common Side Effects

  • Dryness: Tazorac can cause dryness and flaking of the skin, especially during the initial stages of treatment. Using a gentle moisturizer can help alleviate this symptom.
  • Redness: Some individuals may experience mild to moderate redness at the application site. This is a common reaction and should diminish over time.
  • Itching or Irritation: Tazorac may cause itching or irritation, particularly in individuals with sensitive skin. If these symptoms persist or worsen, consult your healthcare provider.
  • Peeling: As Tazorac promotes skin cell turnover, you may notice some peeling. This is a normal part of the treatment process and indicates that the medication is working effectively.
  • Stinging or Burning Sensation: Tazorac may initially cause a stinging or burning sensation upon application. This should subside as your skin adapts to the medication.

Rare Side Effects

  • Allergic Reactions: In rare cases, Tazorac can trigger allergic reactions. Symptoms may include hives, itching, swelling, or difficulty breathing. Seek immediate medical attention if you experience these symptoms.
  • Excessive Irritation: Some individuals may develop severe irritation or a rash at the application site. If you notice persistent or worsening irritation, discontinue use and consult your healthcare provider.
  • Eye Irritation: Tazorac should be kept away from the eyes, as it may cause irritation or redness. If accidental contact occurs, rinse your eyes thoroughly with water and seek medical advice if necessary.
  • Hyperpigmentation or Hypopigmentation: Rarely, Tazorac may cause changes in skin pigmentation. This can manifest as darkening (hyperpigmentation) or lightening (hypopigmentation) of the treated area. If you notice any significant changes in skin color, consult your healthcare provider.
  • Increased Sun Sensitivity: Tazorac can make your skin more sensitive to sunlight. It is crucial to use sunscreen and limit sun exposure during treatment to minimize the risk of sunburn and sun damage.

Severe Side Effects

  • Severe Allergic Reactions: In some rare instances, this medication can cause severe allergic reactions known as anaphylaxis. Symptoms may include difficulty breathing, chest tightness, swelling of the face, lips, tongue, or throat, and dizziness. Call emergency services immediately if you encounter these symptoms.
  • Severe Skin Irritation: While uncommon, Tazorac can cause severe skin irritation characterized by intense redness, blistering, or crusting. Discontinue use and seek medical help promptly if you experience these symptoms.
  • Excessive Dryness or Eczema: Severe dryness or the development of eczema-like symptoms may occur in some individuals. If your skin becomes excessively dry or you notice persistent eczema-like patches, consult your healthcare provider.
  • Eye Problems: Although rare, Tazorac may cause eye-related issues, including blurred vision, eye pain, or swelling. If you experience any eye-related symptoms, seek prompt medical attention.
  • Worsening of Existing Skin Conditions: In rare cases, Tazorac may exacerbate existing skin conditions, such as psoriasis. If your symptoms worsen or new lesions appear, consult your healthcare provider.


Understanding these interactions is crucial for ensuring the safety and effectiveness of your treatment.

Drug Interactions with Tazorac Gel

  • Retinoids: Combining Tazorac gel with other retinoid medications may increase the risk of skin irritation and sensitivity. It is advisable to avoid using multiple retinoid-based products simultaneously.
  • Topical Steroids: Concurrent use of Tazorac gel with topical steroids may lead to increased skin irritation. Your healthcare provider may recommend adjusting the dosage or frequency of application to minimize this risk.
  • Medications with Photosensitizing Effects: Some medications can make your skin more sensitive to sunlight. When combined with Tazorac gel, these medications may increase the risk of sunburn or other skin reactions. It is essential to use adequate sun protection measures and consult your healthcare provider for guidance.

Herbal Interactions with Tazorac Gel

  • St. John’s Wort: This herbal supplement is known to induce the cytochrome P450 enzyme system in the liver. Since Tazorac gel is also metabolized by this enzyme system, combining the two may affect the metabolism and efficacy of Tazorac gel. It is advisable to consult your healthcare provider before using St. John’s Wort with Tazorac gel.
  • Calendula: While Calendula is generally considered safe, it may cause skin irritation when used concurrently with Tazorac gel. Monitor your skin closely for any adverse reactions and discontinue use if necessary.
  • Green Tea: Green tea is often consumed for its antioxidant properties. However, when applied topically or used in combination with Tazorac gel, it may increase the risk of skin irritation. Be mindful of any adverse reactions and adjust your skincare routine accordingly.

Food Interactions with Tazorac Gel

  • Spicy Foods: Spicy foods may cause increased skin sensitivity and irritation when used in conjunction with Tazorac. It is advisable to minimize the consumption of spicy foods or adjust your diet accordingly.
  • Citrus Fruits: Although there is limited evidence, some individuals have reported increased skin irritation when consuming citrus fruits while using Tazorac. If you experience any adverse reactions, it may be worth reducing your intake of citrus fruits.
  • Alcohol: While alcohol itself does not directly interact with Tazorac, it may exacerbate the drying and irritating effects of the medication on the skin. It is advisable to limit alcohol consumption or consult your healthcare provider for guidance.


To ensure the proper and safe use of Tazorac, it is essential to understand its dosing guidelines, including missed doses and overdose.

Initial Dose

Before starting Tazorac. it is essential to consult with your healthcare provider. They will determine the appropriate initial dose based on your specific condition and medical history. The initial dose may vary depending on the severity of your acne or psoriasis and your skin’s sensitivity. It is crucial to follow the prescribed initial dose to avoid potential adverse effects and achieve optimal treatment outcomes.

Recommended Dosing for Tazorac

Once you have started using Tazorac, it is crucial to follow the recommended dosing guidelines. Typically, the recommended dose is to apply a thin layer of the gel to the affected area(s) once daily, preferably in the evening. Gently massage the gel into the skin until it is evenly distributed. Avoid applying the gel to areas of broken or irritated skin, as it may cause further irritation.

To achieve the best results, it is important to use Tazorac consistently. However, the duration of treatment may vary depending on the individual’s response to the medication. Your healthcare provider will determine the appropriate duration of treatment based on your condition.

Missed Doses

If you accidentally miss a dose of Tazorac, do not double the dose to make up for the missed one. Simply resume your regular dosing schedule and apply the gel as directed. It is important to maintain consistent use of Tazorac to achieve the desired therapeutic effects. However, if you have any concerns about missed doses or need further guidance, consult your healthcare provider or pharmacist.


Using more than the prescribed amount of Tazorac or applying it more frequently than recommended can lead to an overdose. If you suspect an overdose, seek immediate medical attention or contact your local poison control center. Symptoms of an overdose may include severe skin irritation, redness, swelling, or other adverse reactions. It is crucial to use Tazorac  strictly according to the prescribed dosing guidelines to minimize the risk of an overdose.


To ensure its effectiveness and longevity, it is crucial to store this gel properly.

  • The Ideal Storage Temperature: Tazorac should be stored at room temperature, preferably between 68°F (20°C) and 77°F (25°C). It is essential to avoid extreme temperatures, as they can impact the stability and efficacy of the gel. Exposing Tazorac to excessive heat or cold can alter its composition, rendering it less effective or even ineffective.
  • Protecting Tazorac from Light: Tazorac is sensitive to light, so it is crucial to store it in a light-protected container. The original packaging serves as an effective shield against light exposure. Ensure that you keep the gel tube or bottle in a dark and cool place, away from direct sunlight. Light can degrade the active ingredients in the gel, reducing its potency.
  • Avoiding Humidity and Moisture: Moisture can affect the consistency and stability of Tazorac. To prevent moisture damage, store the gel in a dry environment. The bathroom might seem like a convenient storage location, but it can expose the gel to humidity due to steam from showers. Instead, opt for a cool and dry area, such as a bedroom or closet, to protect the gel from moisture.
  • Keeping Tazorac Away from Children and Pets: It is essential to store Tazorac in a secure location, out of reach of children and pets. The gel contains active ingredients that can be harmful if ingested. Consider using childproof caps or storing the gel in a locked cabinet or drawer to ensure the safety of those around you.
  • Checking Expiration Dates: Tazorac has an expiration date printed on the packaging. It is crucial to monitor the expiration date and refrain from using the gel beyond that point. Expired medications can lose their efficacy and may even cause adverse effects. Always discard Tazorac that has expired and consult your dermatologist for a new prescription.


While Tazorac is effective in treating acne, it is important to know how to dispose of it properly to ensure the safety of both humans and the environment.

  1. Remove the Tazorac from its original packaging and mix it with an undesirable substance such as coffee grounds or kitty litter.
  2. Place the mixture in a sealed bag or container to prevent leakage.
  3. Dispose of the bag or container in your regular household trash.
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