Trulicity Pens

Trulicity (dulaglutide) is a prescription injectable medication that is used for improving glycemic control in patients who have been diagnosed with type 2 diabetes. It may also be used for some children who are aged at least 10 years or older. This medication may also reduce adult patients’ risk of experiencing major adverse cardiovascular events. There are thousands of patients across the U.S. who trust Insulin Outlet for its easy online ordering and a large selection of name-brand diabetes medications at more affordable prices – as long as they have a valid prescription. We only partner with licensed Canadian pharmacies and we make sure that all patients receive authentic and carefully handled medication at a more accessible price point.

Trulicity is a prescription GLP-1 receptor agonist medication that is used to help patients improve their glycemic control if they have been diagnosed with type 2 diabetes. This medication can help patients lower their A1C and minimize their risk of experiencing cardiovascular events. Trulicity may also lead to weight loss in some patients – although this is not an effect the medication is specifically prescribed to help with. This medication may be used in adult patients or pediatric patients who are at least 10 years of age with type 2 diabetes.

• This medication is safe for use in children aged at least 10 years for blood sugar control if they have been diagnosed with type 2 diabetes
• Trulicity is given in convenient once-weekly doses
• This medication may also be effective for helping adults lower their A1C and risk of experiencing serious cardiovascular events
• Trulicity has also been proven to often cause patients to lose weight while taking it (even though this is only a potential off-label secondary effect and is not approved as weight loss medication)

Trulicity comes in the form of a prefilled pen that contains an injectable solution of the medication. Patients – both pediatric and adult – are usually given a starting dose of 0.75 mg per week to help their bodies adjust to the medication. The injection can be administered at any time of day – with or without meals – as long as it is on the same designated day each week. Children aged 10 and older require particularly close monitoring for systemic side effects during the mandatory four-week dose-escalation phases. A doctor may increase this dose to 1.5 mg once per week for at least four more weeks if the patient’s blood sugar levels remain high. A doctor may also determine that a further dose increase to 3 mg per week may be needed after those four weeks if blood sugar levels need further management. The maximum dose a patient may be prescribed of this medication is 4.5 mg if blood sugar levels remain high after at least four weeks after being on the 3 mg dose. Each of these pens comes prefilled with 0.5 mL of the medication solution.

Patients can take their weekly doses of their medication from their Trulicity pens by:

1. Removing the pen from storage and checking the label/expiration date
2. Checking the pen to make sure it is not damaged and the liquid inside of it is clear/free of particles
3. Thoroughly washing their hands
4. Locating the injection site (this site should be rotated for each injection that is made and must be on the abdomen, thigh, or upper arm)
5. Uncapping the pen
6. Placing the clear base flat against their skin
7. Turning the lock ring to unlock
8. Making the injection by pressing the green button and listening for a click
9. Continuing to hold down the button until a second click is heard (this often takes about 5-10 seconds)
10. Gently lifting the pen away to remove it from the skin
11. Checking to make sure the gray plunger in the pen is able to be seen (indicating that the dose is complete)
12. Disposing of the used pen in a proper sharps container

Each pen is single-use and pens should never be shared between patients. They should also not be used if they become frozen or if the solution does not appear clear. Patients may choose whether or not they take their doses with food.

Trulicity has a boxed warning for being possibly linked to thyroid C-cell tumors. This may include cancer. This possible link was found during rodent testing and how these effects translate to use in humans is still uncertain. This is why patients are told not to take this medication if they themselves or any member of their family have had a history of medullary thyroid carcinoma. The same goes for those with personal or family histories of Multiple Endocrine Neoplasia syndrome type 2. This medication is considered to be contraindicated in both of these populations.

Those who are taking this medication and believe they are experiencing any signs of thyroid tumors – which may include signs such as a lump or swelling in the area of their neck – should seek immediate medical attention. This also includes if the patient starts experiencing side effects such as hoarseness in their voice or trouble swallowing. This medication is also contraindicated in anyone who has experienced prior hypersensitivity reactions to any of the contents of Trulicity.

Clinical trials have shown that pancreatitis may also occur in patients taking this medication in some cases. This medication should not be used if this condition is suspected and it should not be continued if this condition is confirmed. The development of hypoglycemia is also possible when taking this medication if it is being combined with the use of any insulin secretagogue or insulin medications. A reduction in the dose of concomitant insulin or insulin secretagogues is often required to minimize this risk.

Kidney function should be monitored for patients with renal impairment. Monitoring is primarily required when patients experience severe gastrointestinal adverse reactions that could lead to dehydration and acute kidney injury. The severe gastrointestinal effects that may possibly occur from this medication also mean it is not recommended for use in patients with severe gastrointestinal disease – as the use of this medication has not been studied in this group of patients. Trulicity should be avoided in patients with pre-existing severe gastroparesis because it has not been adequately studied in that population. Cardiovascular outcome trials also have found that diabetic retinopathy may occur for some patients taking this medication. However, temporary worsening of retinopathy is actually associated with the rapid improvement of blood glucose levels rather than the medication itself. Patients with diabetic retinopathy in the past should be closely monitored.

Common Side Effects

The side effects of this medication that are most frequently reported by patients are those such as:

• Fatigue
• Indigestion
• Nausea
• Decreased appetite
• Abdominal pain
• Vomiting
• Diarrhea

These side effects are most frequently experienced when the patient starts their medication or around the time of dose increases. Most of these side effects should resolve on their own as the patient’s body gets used to the medication. Patients whose side effects do not go away or whose side effects become severe should seek medical attention.

Severe Side Effects

Serious side effects may also occur for some patients. However, these effects are less frequently reported. These include side effects such as:

• Pancreatitis (patients must immediately stop the drug and seek help if they experience persistent, severe abdominal pain that radiates to the back)
• Gallbladder issues
• Hypoglycemia (more common in those combining the medication with a sulfonylurea or insulin medication)
• Kidney problems (usually caused by dehydration or a loss of fluids while taking this medication)
• Severe stomach issues (that go beyond gastrointestinal intolerance during initiation or dose escalation)
• Hypersensitivity reactions
• Vision changes
• Allergic reactions

Patients experiencing any of the side effects above should seek immediate medical attention.

Those who miss a dose of this medication should take it as soon as they remember – provided there are at least 72 hours remaining before their next scheduled dose. Patients should skip the missed dose if there are fewer than 72 hours remaining before their next scheduled dose and then resume their regular dosing schedule at the next planned time. This strict window is necessary because of the drug’s long 5-day half-life and is intended to prevent dangerous drug accumulation. No additional medication should be taken. Patients who take too much of this medication should get medical attention right away to determine what the next steps are that they should take.

Trulicity pens may be kept in the refrigerator until the expiration date or up to 14 days without refrigeration (as long as temperatures are not greater than 30°C). They must not be stored in the refrigerator again after they have been brought to room temperature. It is preferable that pens be stored in the refrigerator if they are able to be instead of at room temperature. It is important to make sure that they do not become frozen or are kept in any direct light.

Patients buying their medications from Insulin Outlet experience:

• Possible savings of up to 80% compared to U.S. medication prices
• Real medication options from licensed Canadian pharmacies
• Flat $29.99 cold shipping
• Medications and services with a 4.9-star average rating from more than 4,000 users

Buy Trulicity from Canada today.

At Insulin Outlet, we ensure the safety and quality of our medications, meeting all federal legislation standards. Your order will be dispatched from a reputable licensed Canadian pharmacy, guaranteeing the highest standards of reliability and authenticity. This medication has been approved by Health Canada (Canada's FDA) and is identical to what you would receive in the US, only with Canadian labeling and packaging. We do not sell counterfeit or unauthorized medications. Our discounted medications are shipped directly from Canada to your doorstep, providing a fast and secure delivery experience. To conveniently buy Trulicity online at a significant discount, place your order above or call us at 1-888-238-0872.