Zomig Nasal Spray

Starting at $51.95

Zomig Nasal Spray - 2.5mg

Zomig Nasal Spray - 5mg



Zomig Nasal Spray belongs to a class of drugs known as 5-hydroxytryptamine agonists (or “triptans“). This medication treats migraine headaches with or without aura (warning signs that appear before the onset of a migraine headache). The drug relieves headaches, pain, and other migraine symptoms (such as nausea, vomiting, and sensitivity to light and sound). If you receive prompt treatment, you can return to your routine sooner and may not need to take as much pain medication.

It affects a natural substance (serotonin) that narrows blood vessels in the brain. Specific nerves in the brain may also be affected, resulting in pain relief. Using Zolmitriptan does not prevent future migraines or reduce the frequency of migraine attacks. Other types of headaches or headache prevention are not recommended with Zolmitriptan.


Do not use Zomig Nasal Spray if you have or are:

Any of the medication’s ingredients, including zolmitriptan, may cause allergies

You are taking or have recently taken monoamine oxidase (MAO) inhibitors (e.g., phenelzine, tranylcypromine).

Migraine diagnosis is unclear

Having angina (chest pain), including Prinzmetal’s angina (coronary vasospasm).

Having blood vessel disease (e.g., ischemic bowel disease, Raynaud’s syndrome, stroke, transient ischemic attacks [TIAs].

Migraine headaches (such as hemiplegic, basilar, or ophthalmoplegic migraines)

● History of heart attacks

People with heart disease (e.g., people with heart valve disease, people with ischemic heart disease, people with abnormal heart rhythms, people with congenital heart disease)

Hypertension that is severe or uncontrolled

A 5-hydroxytryptamine agonist (e.g., naratriptan, sumatriptan, rizatriptan) was taken within 24 hours before taking this medication

Taking an ergotamine-containing or ergot-type medication within the past 24 hours (such as dihydroergotamine, ergotamine, or methysergide)

Side Effects

It may cause tingling/numbness, nausea, weakness, drowsiness, or dizziness as well as unusual taste, dry mouth, and discomfort in the nose. Tell your doctor or contact one of our pharmacists if any of these effects persist or worsen.

There is a possibility that this medication will raise your blood pressure. Make sure you check your blood pressure regularly and tell your doctor if the results are high.

Immediately notify your doctor if you experience any serious side effects, such as blue fingers/toes/nails or cold hands/feet.

A common side effect of Zolmitriptan is chest/jaw/neck tightness, pain, or pressure that is usually not serious. These side effects are similar to heart attack symptoms, such as chest/jaw/left arm pain, shortness of breath, or unusual sweating. In the event of these or other serious side effects, seek medical attention immediately, including fast/irregular heartbeat, fainting, severe stomach/abdominal pain, bloody diarrhea, and signs of stroke (such as weakness on one side, difficulty speaking, sudden vision changes, confusion).

It is possible for this medication to increase serotonin levels and to cause a very serious condition called serotonin syndrome/toxicity. Taking other drugs that increase serotonin increases the risk, so tell your doctor or pharmacist about all the drugs you take (see Drug Interactions). If you experience any of the following symptoms, seek medical attention immediately: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation or restlessness.

It is rare for this drug to cause a very serious allergic reaction. If you experience any of the following symptoms of a serious allergic reaction, seek medical attention right away: rash, itching/swelling (especially of the face, tongue, or throat), dizziness, or trouble breathing.

There may be other side effects not listed here. Contact your doctor or one of our pharmacist if you notice any other effects not listed above.

Drug Interactions

You may experience severe side effects if you have drug interactions. There are not all possible drug interactions listed in this document. Provide your doctor and pharmacist with a list of all the products you use (including prescriptions, nonprescription, and herbal products). You must get your doctor’s approval before starting, stopping, or changing the dosage of any medicine.

A serious (possibly fatal) drug interaction may occur if MAO inhibitors are taken with this medication. This medication should not be taken with any MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine). Before treatment with this medication, MAO inhibitors should also not be taken for two weeks. It would be best to ask your doctor when to start or stop taking this medication.

Other drugs that increase serotonin increase your risk of serotonin syndrome/toxicity. Many examples of medicines can cause depression, such as MDMA/”ecstasy,” St. John’s wort, and some antidepressants (such as fluoxetine/paroxetine and duloxetine/venlafaxine). When you start or increase the dose of these drugs, you may be more likely to experience serotonin syndrome/toxicity.

To avoid serious side effects, you will need to separate your zolmitriptan dose from your dose of any ergotamine medications (such as dihydroergotamine) or other “triptan” medications (such as sumatriptan rizatriptan). You should consult your doctor before retaking these drugs after a long period.


When a migraine begins, spray one into one nostril as directed by your doctor. Spraying into your eyes is not recommended. Before using this medication, blow your nose gently. Holding one nostril firmly with both hands, remove the protective cap. Inhale gently as you press the plunger of the spray device into the other nostril. Tilt your head back for 5 to 10 seconds, remove the tip from your nose, and breathe gently through your mouth. After using the spray, you may notice a slight taste, and your nose may feel wet. It’s normal to experience this.

Do not take more doses of this medication without consulting your doctor if your symptoms do not improve. You may repeat the amount at least two hours after the first dose if your symptoms are only partially relieved or if your headache returns. In 24 hours, do not exceed 10 milligrams.

Medications you may be taking, your medical condition, and how you respond to treatment determine your dosage. All your products, including prescriptions, nonprescription, and herbal, should be disclosed to your doctor.

Before taking zolmitriptan, your doctor may perform a heart exam if you have a higher risk for heart problems (see Precautions tab). To monitor for serious side effects (such as chest pain), they may also direct you to take your first dose in the office/clinic. For more information, consult your doctor.

Drugs you take for migraine attacks more than ten days a month may worsen your headaches (medication overuse headache). Do not use medications more often or for longer than prescribed. Consult your doctor if you need to use this medication more frequently, if it doesn’t work as well, or if your headaches worsen.


If someone is overdosing and has severe symptoms like passing out or difficulty breathing, call 911 immediately. Otherwise, contact a poison control center directly. Residents of the US can contact their local poison control center at 1-800-222-1222.


Children and pets should not be allowed to access this product.

You should store the product between 68 and 77 degrees Fahrenheit (20 to 25 degrees C). After the expiration date, discard any medication that has not been used.

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