Breo Ellipta

Breo Ellipta can increase the risk of asthma-related deaths and should only be used in patients not adequately controlled on long-term asthma control medication. The medication may also cause serious cardiovascular events and should be used with caution in patients with cardiovascular disease. Regular monitoring of lung function and cardiovascular status is recommended.

You should inform your doctor or pharmacist if you have any allergies to fluticasone or vilanterol. There is a possibility that this product contains inactive ingredients (such as milk proteins), which may cause allergic reactions. Talk to your pharmacist for more details.

Tell your doctor or pharmacist about your medical history before taking this medication, especially if you suffer from high blood pressure, bone loss (osteoporosis), depression, diabetes, eye problems (cataracts, glaucoma), heart problems (angina, irregular heartbeat), a recent infection, liver problems, hyperthyroidism, seizures.

There is a possibility that fluticasone/vilanterol may cause a condition that affects the heart rhythm (QT prolongation). It is rare for QT prolongation to cause serious (rarely fatal) fast/irregular heartbeats and other symptoms (such as severe dizziness, fainting) that require immediate medical attention.

Certain medical conditions or drugs that may cause QT prolongation may increase your risk of QT prolongation. Tell your doctor or pharmacist about all medications you take before taking fluticasone/vilanterol, as well as any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).

You may also be at risk of QT prolongation if you have low potassium or magnesium levels in your blood. The risk may increase if you use certain drugs (such as diuretics/”water pills”) or if you suffer from conditions such as severe sweating, diarrhea, or vomiting. Consult your doctor before using fluticasone/vilanterol.

It may be harder for your body to respond to physical stress if you have switched from a corticosteroid taken by mouth (such as prednisone tablets) to this inhaler within the past 12 months, or if you have been using it in high doses for a long time. In case of a serious illness or injury, tell your doctor or dentist that you are taking this medication or have taken a corticosteroid by mouth within the past 12 months before having surgery or emergency treatment. If you feel unusually tired or lose weight, tell your doctor as soon as possible. Make sure you have a medical ID bracelet or warning card that states you use (or have used) corticosteroids.

Be sure to tell your doctor or dentist about all the products you use (including prescription and nonprescription medications).

Fluticasone/vilanterol may increase your risk of getting an infection or worsen an existing infection. Keep away from people who have infections that can spread to others (e.g. chicken pox, measles, flu). If you have been exposed to an infection or would like more information, contact your doctor.

A child’s growth may be temporarily slowed down if this medication is taken for an extended period of time. Growth can also be slowed down by poorly controlled asthma. Regularly check your child’s height with the doctor.

This drug may cause QT prolongation in older adults, which is more common in older adults.

Pregnant women should only use this medication when clearly necessary. Consult your doctor about the risks and benefits. There is no information on whether this medication passes into breast milk. It is known, however, that similar drugs pass into breast milk. Consult your doctor before breast-feeding. See pregnancy tab for more information. 

Follow your doctor’s instructions exactly when using Breo Ellipta inhalation powder. Make sure you follow all directions on your prescription label and read all medication guides and instructions. There may be times when your doctor changes your dosage.

For asthma or bronchospasm attacks, Breo Ellipta is not a rescue medicine. A fast-acting inhalation medicine should be used during an attack. Whenever your breathing problems worsen or if your asthma medication does not seem to be helping, seek medical attention.

Breo Ellipta is a powder that comes with an inhaler that contains blister packs preloaded with measured doses of the medicine. Breo Ellipta blisters are loaded into the inhaler each time it is used. Inhaler instructions should be followed.

Don’t take the medicine more than once in a 24-hour period, and use it at the same time each day.

Surgery, illness, stress, or a recent asthma attack may change your dose needs. Your doctor should be consulted before changing your Breo Ellipta dose or dosage schedule.

The inhaler device should always be rinsed out after use, to prevent thrush (a fungal infection in the mouth or throat).

Your doctor will need to monitor your lung function regularly while you are using Breo Ellipta. It may also be necessary to check your vision and bone mineral density.

Breo Ellipta may be stopped once your asthma has been controlled by your doctor. Do not stop using the medicine unless your doctor tells you to. Keep all follow-up appointments.

The drug is usually started at a low dosage by your doctor. To reach the right dosage for you, they will adjust it over time. In the end, they’ll prescribe the smallest dose that provides the desired effect.

The following information describes commonly used or recommended dosages. Make sure you take the dosage your doctor prescribes. Depending on your needs, your doctor will determine the best dosage.

The Breo inhaler is a disposable light gray and blue device. There are two foil blister strips of powder medication in the inhaler:

● Fluticasone furoate is contained in each blister in either 100 mcg or 200 mcg doses.

● Each blister contains 25 mcg of vilanterol trifenatate.

For a total of 30 doses, each strip contains 30 blisters. When you fully open the inhaler cover, a new dose is ready.

COPD Dosage

For chronic obstructive pulmonary disease (COPD), Breo 100/25 once a day is the only recommended dosage. Fluticasone furoate is 100 mcg in one dose, along with vilanterol trifenatate is 25 mcg.

Breo should be inhaled once a day through your mouth using your inhaler. It should be taken at the same time every day. Use it no more than once every 24 hours.

Asthma Dosage

To help prevent asthma attacks, here are two possible doses of Breo:

● Breo 100/25: Fluticasone furoate is 100 mcg per tablet and vilanterol trifenatate is 25 mcg per tablet.

● Breo 200/25: Each dose contains 200 mcg of fluticasone furoate and 25 mcg of vilanterol trifenatate.

Inhale the drug once a day through your mouth using your inhaler. It should be taken at the same time every day. A 24-hour period is the maximum amount of time you should use it.

One inhalation of Breo 200/25 per day is the maximum dose for asthma. Breo 200/25 may be prescribed by your doctor if you are taking Breo 100/25 and need a higher In case of asthma symptoms between doses, take a short-acting beta2-adrenergic agonist (SABA).SABA). You may feel relief immediately.

Visit the drug maker’s website for a video explaining how to use Breo. The following instructions should be followed when taking Breo. Follow your doctor’s or healthcare provider’s instructions when taking the drug.

Remove the inhaler from the package if you are using it for the first time. Follow the steps below.

Inhalers should not be opened and closed unless you are going to use them. If you do not inhale at that time, you will lose the dose. There are no double doses or extra doses that can be taken with one inhalation. (Lost doses are kept in the inhaler, but can no longer be taken.)

Step 1. Dose preparation

● Open the inhaler cover until you hear a click.

● When the cover clicks open, the counter must count down before a dose is prepared. Get in touch with your pharmacist or physician if this happens.

Step 2. A dose is inhaled

● Make sure your fingers aren’t covering the air vents when holding the inhaler.

● Exhale fully, but not into the inhaler.

● Place the mouthpiece of the inhaler in your mouth and close your lips tightly.

●Through your mouth, take a steady, deep breath. Breathe through your mouth instead of your nose.

● For three to four seconds, hold your breath while moving the inhaler away from your mouth.

● Slowly exhale.

Step 3. Rinse your mouth and reset the inhaler

● Before closing the cover, wipe the mouthpiece with a dry tissue. After that, slide the cover all the way back.

● After taking your dose, rinse your mouth with water. After drinking the water, spit it out. Avoid swallowing.

There are many medications that can cause side effects. An unwanted side effect occurs when a medication is taken in normal doses. In addition to mild and severe side effects, temporary and permanent side effects can also occur.

Not everyone who takes this medication experiences the side effects listed below. Discuss the risks and benefits of this medication with your doctor if you are concerned about side effects.

This medication has been reported to cause the following side effects by at least 1% of people who take it. There are many ways to manage these side effects, and some may even disappear on their own over time.

In case of severe or bothersome side effects, contact your doctor. You may be able to get advice on managing side effects from your pharmacist.

● Pain in the abdomen

● Feeling anxious

● Pain in the back

● Coughing

● Feeling dizzy

● The flu

● Migraine

● Blockage, itching, or runny nose

● Pain in the joints

● Muscle spasms

● Back of the mouth pain and irritation

● Hoarseness of the voice

If you do not check with your doctor or seek medical attention, many of the side effects listed below could have serious consequences.

If you experience any of the following side effects, contact your doctor immediately:

● Osteoporosis (bone pain or fractures). Inform your doctor if you are taking medications such as Prolia for treatment.

● The symptoms of the flu (loss of energy, fever, cough, sore throat) include rash, pins and needles sensation, and worsening breathing difficulties

● An increase in blood pressure

● An irregular or increased heartbeat

● Symptoms of electrolyte imbalance (e.g., muscle cramps, weakness, irregular heartbeat)

● Symptoms of pneumonia (e.g., fever, chills, shortness of breath, coughing)

● A corticosteroid overdose is characterized by rapid weight gain, sweating, thinning skin, dry skin, and muscle weak

● A sinus infection or a throat infections

● The symptoms of cataracts include cloudy vision, blurry vision, and eye pain.

● Common cold symptoms (e.g., sinus congestion, runny nose, sore throat, general feeling of unwellness)

● Shortness of breath, coughing, chest discomfort, coughing up mucus are symptoms of COPD.

● Symptoms of high blood sugar include frequent urination, increased thirst, excessive eating, unexplained weight loss, poor wound healing, infections, and fruity breath odor.

● The symptoms of glaucoma are blurred vision, halos of bright colors around lights, red eyes, increased pressure in your eyes, and eye pain or discomfort.

● Thrush symptoms (sore, raised patches in the mouth)

In the event of any of the following symptoms, stop taking the medication and seek immediate medical attention:

● A serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea, vomiting, or swelling of the face and throat). More information in the next tab. 

● Following the use of the medication, sudden shortness of breath or wheezing may occur

Other side effects may occur in some people. If you notice any symptom that worries you while taking this medication, contact your doctor.

Breo can cause an allergic reaction in some people, as it does with most drugs. Mild allergic reactions can cause the following symptoms:

● A rash on the skin

● Itching

● Skin flushing (warmth and redness)

There is a possibility of a more severe allergic reaction, but it is rare. Severe allergic reactions can cause the following symptoms:

● Angioedema (swelling under your skin, usually in your eyes, lips, hands, or feet)

● A swelling of the tongue, mouth, or throat

● Breathing problems

In case of a severe allergic reaction to Breo, contact your doctor immediately. In case of an emergency, call 911 if you feel your symptoms are life-threatening.

You may experience serious side effects if you have drug interactions that change how your medications work. There may be other drug interactions not listed in this page. Inform your doctor about all the products you use (including prescription/nonprescription drugs and herbal products). Your doctor should be consulted before beginning, stopping, or changing the dosage of any medication.

There are other medications that may affect the removal of fluticasone from your body, which may affect fluticasone’s effectiveness. Some azole antifungals (such as ketoconazole) and HIV protease inhibitors (like lopinavir and ritonavir) are examples.

You should call 911 if someone has overdosed and has serious symptoms such as passing out or difficulty breathing. In any other case, contact a poison control center immediately. Residents of the United States can reach their local poison control center at 1-800-222-1222. Overdose symptoms include chest pain, fast heartbeat, tremors (shaking).

Breo should be administered as soon as you remember if you miss a dose. One inhalation per day is all you should take. The next dose should be taken at the usual time. Do not increase your next dose or take an extra dose to catch up. There can be dangerous side effects from this.

The product should be stored between 68°F and 77°F (20°C and 25°C); excursions are allowed between 59°F and 86°F (15°C to 30°C). Avoid direct sunlight and heat. Store in a dry place. Children should not be allowed to play with this product.

Breo Ellipta should be stored in its unopened moisture-protective foil tray and only be removed from the tray right before use. Breo Ellipta should be discarded 6 weeks after opening the foil tray or when the counter reads “0” (after all blisters have been consumed). It is not possible to reuse the inhaler. Inhalers should not be disassembled.

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