Xenical (Orlistat)

Xenical can cause severe liver injury and patients should be monitored for signs of liver damage, such as jaundice or dark urine. It may also increase the risk of cholelithiasis and malabsorption of fat-soluble vitamins. Patients should take a multivitamin supplement to ensure adequate nutrition.

In case of digestive disorders (problems absorbing food), this medicine should not be taken. Pregnant women and those with gallbladder problems should not take Xenical. If you have had an organ transplant, are using cyclosporine, or are not overweight, do not use it.

Xenical is only part of a comprehensive treatment program that includes diet, exercise, and weight control. All of your daily meals should have an equal amount of fat, protein, and carbohydrates. Make sure you follow your diet, medication, and exercise routines closely.

Fat-rich diets should be avoided. It is possible to experience unpleasant side effects from Xenical if you consume high-fat meals together with it.

Be sure to mention to your prescriber if you are a diabetic and are taking insulin.

You may experience worse side effects if you eat more fat than you should. Do not hesitate to contact your doctor if these effects persist or worsen.

Your doctor prescribes this medication because they deem that the benefits to you outweigh any risks it may pose. There are a few severe side effects associated with this medication.

Tell your doctor right away if you experience any serious side effects, including nausea/vomiting that won’t stop, severe stomach/abdominal pain, dark urine, yellowing eyes/skin, symptoms of liver disease (such as nausea/vomiting that doesn’t stop, severe stomach/abdominal pain, dark urine, yellowing eyes/skin), symptoms of kidney stones (such as back pain, pain when urinating, pink/bloody urine).

It is rare for this drug to cause a very serious allergic reaction. In any case, seek medical attention immediately if you experience any symptoms of a severe allergic reaction, such as a rash, itching/swelling (especially of the face/mouth/throat), severe dizziness, or trouble breathing.

The following is a partial list of possible side effects. If you have any questions about the medication and feel the need to speak to a licensed pharmacist, please do not hesitate to contact us. 

Unabsorbed fat often causes changes in bowel function. Symptoms may include:

• fatty/oily stool,
• oily spotting,
• intestinal gas with discharge,
• urinating immediately,
• more frequent bowel movements or
• poor bowel control

Xenical can be prescribed for adults, as well as children over the age of 12 for weight-loss treatment.

Adult Obesity Dose

A dose of 120 mg should be taken orally three times a day with each main meal containing fat. It may be taken during a meal or within an hour of finishing one.

Pediatric Dose (12 years or older)

A dose of 120 mg should be taken orally three times a day with each main meal containing fat. It may be taken during a meal or within an hour of finishing one.

The following list needs to be more comprehensive. Prescription and over-the-counter medications, vitamins, and herbal products may interact with orlistat. This webpage does not list all possible interactions.

If you are also taking any of the following medications, ask your doctor or pharmacist whether Xenical is safe for you to use.

• Amiodarone;
• Diabetes medicine (such as Jardiance) or insulin (such as Humalog);
• HIV or AIDS medications;
• Medicine for seizures 
• a vitamin/mineral supplement that has beta-carotene or vitamin E; 
• A blood thinner such as Eliquis, Xarelto, or Jantoven.

Overdose symptoms such as passing out or trouble breathing should be reported to 911 immediately.Otherwise, contact a poison control center immediately.Call 1-800-222-1222 to reach your local poison control center.

Missed doses should be taken as soon as you remember, unless it has been more than 1-2 hours since your last meal. As a result, you should skip the missed dose since most of the fat in your meal has already been absorbed and the medication will not work. Trying to catch up should not be done by doubling the dose.

You or your child’s doctor should check your or their progress at regular visits to ensure that this medicine is working as expected. In order to check for unwanted effects, blood and urine tests may be required.

It is possible to harm your unborn baby if you take this medicine while you are pregnant. Keeping yourself from getting pregnant requires effective birth control. You should tell your doctor right away if you think you have become pregnant while using this medicine.

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