Dexilant (Dexlansoprazole)

Long-term use of Dexilant may be associated with an increased risk of Clostridium difficile-associated diarrhea, bone fractures, and hypomagnesemia. Patients should be monitored for these conditions, especially those at higher risk for bone fractures and electrolyte imbalances.

Dexilant can cause kidney problems. In case of decreased urination or blood in the urine, speak to your doctor.

Diarrhea may indicate a new infection. You should contact your doctor if your diarrhea is watery or contains blood.

Dexilant may exacerbate or cause new symptoms of lupus. Symptoms that worsen in sunlight include joint pain and a rash on your cheeks or arms.

Long-term use or taking Dexilant more than once daily may increase your risk of breaking a bone.

Early symptoms of a heart attack can be mimicked by heartburn. If you feel anxious or lightheaded and have chest pain that spreads to your jaw or shoulder, seek emergency medical help.

Taking this medicine can cause breathing difficulties, kidney problems, or severe allergic reactions if you are allergic to Dexilant. Taking this medicine is not recommended if you take a pill containing rilpivirine (Complera, Edurant, Odefsey).

Tell your doctor if you have had severe liver disease, osteoporosis, low bone mineral density (osteopenia), or low magnesium levels.

Taking a proton pump inhibitor long-term or more than once a day may make you more likely to break a hip, wrist, or spine. Keep your bones healthy by talking to your doctor.

Before taking dexlansoprazole and, each time you get a refill, read the Medication Guide and, if available, the Patient Information Leaflet provided to you within the delivery. Your doctor or pharmacist can answer any questions you may have.

As directed by your doctor, take this medication once daily by mouth with or without food. For best results, your doctor may require you to take your dose every day before the same meal if your symptoms usually occur after a meal. Based on your medical condition and treatment response, the treatment dosage and duration will be determined.

The capsules should not be crushed or chewed. This medication should be swallowed whole. If you have trouble swallowing this medication, it may be helpful if you open the capsule and sprinkle the contents onto one tablespoon (15 milliliters) of applesauce. The drug/food mixture should be swallowed immediately without chewing. Preparing the mix in advance is not recommended. The drug may be destroyed if you do so.

Ask your health care professional how to properly mix and administer the drug if you give it with a liquid medication measuring device/syringe or through a stomach tube (nasogastric or gastric tube). This medication may be taken with antacids if necessary. Dexlansoprazole should be taken at least 30 minutes before sucralfate if you are also taking it. If you require further assistance, feel free to contact us and we can put you in touch with one of our licensed pharmacists.

To get the most benefit from this medication, use it regularly. It would help if you took it every day at the same time to help you remember. Even if you feel better, take this medication for the prescribed length.

If your condition persists or worsens, tell your doctor. Over time, side effects become more likely. If you are taking this medication, ask your doctor how long you should take it.

There is a possibility of diarrhea. Tell your doctor if this effect persists or gets worse.

The reason for prescribing this medication is that your doctor believes the benefit to you outweighs the side effects. There are few serious side effects associated with this medication.

Any serious side effects should be reported to your doctor immediately, such as: symptoms of a low magnesium blood level (such as muscle spasms, irregular heartbeats, seizures), signs of lupus (such as rash on nose or cheeks, new or worsening joint pain).

It is possible for this medication to cause a severe intestinal condition due to a bacteria known as Clostridium difficile. During or after treatment, this condition can occur. Symptoms of diarrhea that doesn’t stop, abdominal pain/cramping, blood/mucus in your stool should be reported to your doctor as soon as possible.

It is best not to use anti-diarrhea products or opioids if you are experiencing these symptoms.

There have been rare cases of vitamin B-12 deficiency caused by proton pump inhibitors (such as dexlansoprazole). Taking them every day for a long period of time (3 years or more) increases the risk. In case of unusual weakness, sore tongue, or numbness/tingling of hands or feet, notify your doctor immediately.

It is rare for this drug to cause a very serious allergic reaction. If you notice any signs of a serious allergic reaction, such as fever, swollen lymph nodes, rash, itching/swelling, dizziness, difficulty breathing, signs of kidney problems (such as change in urine amount), get medical help right away.

There may be other side effects not listed here. Consult your doctor if you notice any other effects not listed above.

For medical advice about side effects in the US, contact your doctor. FDA can be contacted at 1-800-FDA-1088 or at www.fda.gov/medwatch for reports of side effects.

Your medications may not work as well as they should, or you may experience severe side effects due to drug interactions. The list of possible drug interactions in this document is incomplete. Share with your doctor a list of your products (including prescriptions, nonprescriptions, and herbal products). With your doctor’s approval, start, stop, or change the dosage of any medicines.

This drug can interact with methotrexate (particularly in high-dose treatment).

For some products to be adequately absorbed by the body, stomach acid is needed. In addition to decreasing stomach acid, dexlansoprazole may affect the effectiveness of these products. Ampicillin, atazanavir, erlotinib, levoketoconazole, nelfinavir, Pazopanib, rilpivirine, sparsentan, and certain azole antifungals (itraconazole, ketoconazole, posaconazole) are some of the affected products.

There is a great deal of similarity between dexlansoprazole and lansoprazole. Dexlansoprazole should not be taken with medications containing lansoprazole.

The use of Dexilant during pregnancy has not been evaluated in clinical trials. Nevertheless, studies have looked at whether other proton pump inhibitors (PPIs) are safe during pregnancy. A review of 60 studies found that PPIs did not cause birth defects during pregnancy (Dexilant is a PPI.)

The use of Dexilant in pregnant animals was found to be safe even at high doses. There are, however, some differences between studies conducted on animals and those conducted on humans.

Pregnant women or those preparing for pregnancy should tell their doctors that they’re taking Dexilant. Dexilant can cause pregnancy, so tell your doctor if you become pregnant while taking it. During pregnancy, they can determine if Dexilant is safe for you to take.

The symptoms of an overdose include high blood pressure, weight loss, hot flashes, bruising, and pain in the mouth and throat.

Call your doctor if you think you’ve taken too much Dexilant. They can prescribe medication to treat your symptoms and monitor your condition if necessary.

The American Association of Poison Control Centers can also be reached at 800-222-1222.

Depending on how and where you store Dexilant, the medication can last for a long time.

You should store Dexilant capsules at room temperature between 68°F and 77°F (20°C and 25°C). Short-term storage of Dexilant is possible at temperatures between 59°F and 86°F (15°C and 30°C).

Dexilant should be stored in a tightly sealed container. The best place to store Dexilant is away from damp or wet areas, such as bathrooms.

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